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|
| 27.11.2021 | 21:00 | Talleres de Córdoba | - | Aldosivi | 2:0 (0:0) | |
| 23:15 | Patronato de Paraná | - | Godoy Cruz | 0:3 (0:1) | ||
| 28.11.2021 | 01:30 | Estudiantes | - | Vélez Sarsfield | 1:0 (1:0) | |
| 21:00 | Rosario Central | - | River Plate | 2:2 (1:0) | ||
| 23:15 | Argentinos Juniors | - | Gimnasia de La Plata | 3:0 (1:0) | ||
| 23:15 | Defensa y Justicia | - | Colón de Santa Fe | 1:1 (0:0) | ||
| 29.11.2021 | 21:00 | Unión de Santa Fe | - | Atlético Tucumán | 3:0 (2:0) | |
| 23:15 | Racing Club | - | CA Lanús | 3:1 (2:1) | ||
| 30.11.2021 | 01:30 | Central Córdoba SdE | - | Arsenal de Sarandí | 5:0 (3:0) | |
| 01:30 | Platense | - | Huracán | 4:2 (2:1) | ||
| 21:00 | San Lorenzo | - | Sarmiento de Junín | 1:0 (1:0) | ||
| 23:15 | Boca Juniors | - | Newell's Old Boys | 0:0 (0:0) | ||
| 01.12.2021 | 01:30 | Banfield | - | Independiente | 4:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate | 23 | 16 | 5 | 2 | 50:15 | 35 | 53 |
| 2 |
|
Talleres de Córdoba | 23 | 13 | 4 | 6 | 35:25 | 10 | 43 |
| 3 |
|
Defensa y Justicia | 23 | 11 | 8 | 4 | 38:21 | 17 | 41 |
| 4 |
|
Vélez Sarsfield | 23 | 10 | 8 | 5 | 32:18 | 14 | 38 |
| 5 |
|
Estudiantes | 23 | 10 | 8 | 5 | 37:24 | 13 | 38 |
| 6 |
|
Boca Juniors | 23 | 10 | 7 | 6 | 26:17 | 9 | 37 |
| 7 |
|
CA Lanús | 23 | 10 | 6 | 7 | 41:39 | 2 | 36 |
| 8 |
|
Colón de Santa Fe | 23 | 10 | 6 | 7 | 23:28 | -5 | 36 |
| 9 |
|
Independiente | 23 | 9 | 7 | 7 | 24:22 | 2 | 34 |
| 10 |
|
Gimnasia de La Plata | 23 | 9 | 7 | 7 | 23:24 | -1 | 34 |
| 11 |
|
Huracán | 23 | 8 | 8 | 7 | 23:24 | -1 | 32 |
| 12 |
|
Rosario Central | 23 | 9 | 4 | 10 | 36:35 | 1 | 31 |
| 13 |
|
Unión de Santa Fe | 23 | 9 | 4 | 10 | 29:30 | -1 | 31 |
| 14 |
|
Godoy Cruz | 23 | 8 | 6 | 9 | 32:29 | 3 | 30 |
| 15 |
|
Racing Club | 23 | 7 | 8 | 8 | 22:21 | 1 | 29 |
| 16 |
|
Argentinos Juniors | 23 | 7 | 8 | 8 | 22:22 | 0 | 29 |
| 17 |
|
Platense | 23 | 6 | 9 | 8 | 31:32 | -1 | 27 |
| 18 |
|
Newell's Old Boys | 23 | 7 | 6 | 10 | 22:29 | -7 | 27 |
| 19 |
|
Aldosivi | 23 | 8 | 3 | 12 | 23:35 | -12 | 27 |
| 20 |
|
Banfield | 23 | 5 | 10 | 8 | 20:25 | -5 | 25 |
| 21 |
|
Sarmiento de Junín | 23 | 6 | 6 | 11 | 22:29 | -7 | 24 |
| 22 |
|
Central Córdoba SdE | 23 | 5 | 8 | 10 | 27:28 | -1 | 23 |
| 23 |
|
San Lorenzo | 23 | 6 | 5 | 12 | 19:30 | -11 | 23 |
| 24 |
|
Patronato de Paraná | 23 | 5 | 8 | 10 | 23:35 | -12 | 23 |
| 25 |
|
Atlético Tucumán | 23 | 5 | 6 | 12 | 21:42 | -21 | 21 |
| 26 |
|
Arsenal de Sarandí | 23 | 4 | 7 | 12 | 11:33 | -22 | 19 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Copa Libertadores | |
| Copa Libertadores | |
| Copa Sudamericana | |
| Copa Sudamericana | |
| Copa Sudamericana |
