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| 13.05.2023 | 01:00 | Huracán | - | Godoy Cruz | 0:0 (0:0) | |
| 02:30 | Atlético Tucumán | - | Argentinos Juniors | 1:2 (1:1) | ||
| 20:30 | Independiente | - | Tigre | 2:1 (1:1) | ||
| 23:00 | Banfield | - | San Lorenzo | 1:2 (1:1) | ||
| 14.05.2023 | 01:30 | Instituto de Córdoba | - | Colón de Santa Fe | 1:0 (0:0) | |
| 01:30 | Newell's Old Boys | - | Arsenal de Sarandí | 2:0 (1:0) | ||
| 19:00 | Defensa y Justicia | - | Estudiantes | 1:1 (1:1) | ||
| 21:30 | Platense | - | Racing Club | 3:0 (2:0) | ||
| 15.05.2023 | 00:00 | Boca Juniors | - | Belgrano | 2:0 (0:0) | |
| 02:30 | Talleres de Córdoba | - | River Plate | 2:1 (0:0) | ||
| 20:30 | Barracas Central | - | Central Córdoba SdE | 2:2 (0:2) | ||
| 20:30 | Unión de Santa Fe | - | Sarmiento de Junín | 0:2 (0:1) | ||
| 23:00 | Gimnasia de La Plata | - | CA Lanús | 1:0 (0:0) | ||
| 16.05.2023 | 01:30 | Vélez Sarsfield | - | Rosario Central | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate | 16 | 12 | 1 | 3 | 27:8 | 19 | 37 |
| 2 |
|
San Lorenzo | 16 | 9 | 5 | 2 | 17:6 | 11 | 32 |
| 3 |
|
Talleres de Córdoba | 16 | 9 | 3 | 4 | 29:15 | 14 | 30 |
| 4 |
|
Defensa y Justicia | 16 | 8 | 5 | 3 | 21:9 | 12 | 29 |
| 5 |
|
Estudiantes | 16 | 8 | 4 | 4 | 19:14 | 5 | 28 |
| 6 |
|
Rosario Central | 16 | 7 | 6 | 3 | 23:19 | 4 | 27 |
| 7 |
|
Belgrano | 16 | 8 | 3 | 5 | 14:13 | 1 | 27 |
| 8 |
|
CA Lanús | 16 | 7 | 5 | 4 | 23:16 | 7 | 26 |
| 9 |
|
Argentinos Juniors | 16 | 6 | 5 | 5 | 21:15 | 6 | 23 |
| 10 |
|
Godoy Cruz | 16 | 6 | 5 | 5 | 18:18 | 0 | 23 |
| 11 |
|
Newell's Old Boys | 16 | 6 | 5 | 5 | 14:14 | 0 | 23 |
| 12 |
|
Sarmiento de Junín | 16 | 6 | 4 | 6 | 18:15 | 3 | 22 |
| 13 |
|
Boca Juniors | 16 | 6 | 3 | 7 | 20:16 | 4 | 21 |
| 14 |
|
Tigre | 16 | 5 | 6 | 5 | 17:18 | -1 | 21 |
| 15 |
|
Gimnasia de La Plata | 16 | 6 | 3 | 7 | 16:23 | -7 | 21 |
| 16 |
|
Platense | 16 | 5 | 5 | 6 | 18:21 | -3 | 20 |
| 17 |
|
Instituto de Córdoba | 16 | 5 | 5 | 6 | 14:19 | -5 | 20 |
| 18 |
|
Central Córdoba SdE | 16 | 5 | 4 | 7 | 12:18 | -6 | 19 |
| 19 |
|
Barracas Central | 16 | 4 | 6 | 6 | 15:20 | -5 | 18 |
| 20 |
|
Racing Club | 16 | 5 | 3 | 8 | 19:26 | -7 | 18 |
| 21 |
|
Vélez Sarsfield | 16 | 3 | 8 | 5 | 16:15 | 1 | 17 |
| 22 |
|
Independiente | 16 | 3 | 8 | 5 | 15:18 | -3 | 17 |
| 23 |
|
Colón de Santa Fe | 16 | 3 | 8 | 5 | 14:17 | -3 | 17 |
| 24 |
|
Huracán | 16 | 4 | 5 | 7 | 15:20 | -5 | 17 |
| 25 |
|
Banfield | 16 | 3 | 6 | 7 | 10:19 | -9 | 15 |
| 26 |
|
Atlético Tucumán | 16 | 2 | 8 | 6 | 13:20 | -7 | 14 |
| 27 |
|
Arsenal de Sarandí | 16 | 3 | 2 | 11 | 12:24 | -12 | 11 |
| 28 |
|
Unión de Santa Fe | 16 | 1 | 7 | 8 | 9:23 | -14 | 10 |
| Copa Libertadores |
