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| 10.08.2022 | 15:00 | Independiente II | - | Lanús II | 1:2 (1:1) | |
| 16:00 | Central Córdoba SdE II | - | Atlético Tucumán II | 0:3 (0:1) | ||
| 16:00 | Arsenal de Sarandí II | - | Colón de Santa Fe II | 0:1 (0:0) | ||
| 16:00 | Sarmiento de Junín II | - | Huracán II | 3:1 (2:0) | ||
| 11.08.2022 | 15:00 | Boca Juniors II | - | Racing Club II | 3:0 (1:0) | |
| 16:00 | Barracas Central II | - | Rosario Central II | 0:3 (0:1) | ||
| 16:00 | Newell's Old Boys II | - | River Plate II | 2:0 (1:0) | ||
| 16:00 | Aldosivi II | - | Godoy Cruz II | 2:1 (0:1) | ||
| 12.08.2022 | 15:00 | San Lorenzo II | - | Patronato de Paraná II | 1:2 (0:0) | |
| 15:00 | Banfield II | - | Platense II | 0:0 (0:0) | ||
| 16:00 | Unión de Santa Fe II | - | Argentinos Juniors II | 1:1 (1:1) | ||
| 16:00 | Gimnasia de La Plata II | - | Vélez Sarsfield II | 1:0 (0:0) | ||
| 13.08.2022 | 15:00 | Tigre II | - | Defensa y Justicia II | 2:3 (1:2) | |
| 16:00 | Talleres de Córdoba II | - | Estudiantes II | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate II | 13 | 9 | 0 | 4 | 19:10 | 9 | 27 |
| 2 |
|
Newell's Old Boys II | 13 | 7 | 5 | 1 | 19:9 | 10 | 26 |
| 3 |
|
Boca Juniors II | 13 | 8 | 1 | 4 | 20:10 | 10 | 25 |
| 4 |
|
Rosario Central II | 13 | 7 | 3 | 3 | 27:15 | 12 | 24 |
| 5 |
|
Vélez Sarsfield II | 13 | 7 | 2 | 4 | 25:9 | 16 | 23 |
| 6 |
|
Huracán II | 13 | 7 | 2 | 4 | 24:21 | 3 | 23 |
| 7 |
|
Defensa y Justicia II | 13 | 7 | 2 | 4 | 15:14 | 1 | 23 |
| 8 |
|
Argentinos Juniors II | 13 | 6 | 4 | 3 | 21:14 | 7 | 22 |
| 9 |
|
Gimnasia de La Plata II | 13 | 6 | 3 | 4 | 20:15 | 5 | 21 |
| 10 |
|
Tigre II | 13 | 6 | 3 | 4 | 15:15 | 0 | 21 |
| 11 |
|
Independiente II | 13 | 5 | 3 | 5 | 20:17 | 3 | 18 |
| 12 |
|
Atlético Tucumán II | 13 | 5 | 3 | 5 | 20:19 | 1 | 18 |
| 13 |
|
Central Córdoba SdE II | 13 | 5 | 3 | 5 | 12:15 | -3 | 18 |
| 14 |
|
Racing Club II | 13 | 4 | 5 | 4 | 22:15 | 7 | 17 |
| 15 |
|
Arsenal de Sarandí II | 13 | 4 | 5 | 4 | 13:10 | 3 | 17 |
| 16 |
|
Unión de Santa Fe II | 13 | 4 | 5 | 4 | 12:12 | 0 | 17 |
| 17 |
|
Colón de Santa Fe II | 13 | 4 | 5 | 4 | 11:18 | -7 | 17 |
| 18 |
|
Lanús II | 13 | 5 | 1 | 7 | 22:27 | -5 | 16 |
| 19 |
|
Aldosivi II | 13 | 5 | 1 | 7 | 23:31 | -8 | 16 |
| 20 |
|
Banfield II | 13 | 4 | 3 | 6 | 10:13 | -3 | 15 |
| 21 |
|
San Lorenzo II | 13 | 4 | 2 | 7 | 17:20 | -3 | 14 |
| 22 |
|
Estudiantes II | 13 | 3 | 5 | 5 | 10:15 | -5 | 14 |
| 23 |
|
Patronato de Paraná II | 13 | 4 | 2 | 7 | 12:22 | -10 | 14 |
| 24 |
|
Godoy Cruz II | 13 | 3 | 4 | 6 | 14:20 | -6 | 13 |
| 25 |
|
Platense II | 13 | 2 | 6 | 5 | 10:14 | -4 | 12 |
| 26 |
|
Talleres de Córdoba II | 13 | 3 | 3 | 7 | 14:20 | -6 | 12 |
| 27 |
|
Sarmiento de Junín II | 13 | 3 | 2 | 8 | 11:23 | -12 | 11 |
| 28 |
|
Barracas Central II | 13 | 3 | 1 | 9 | 6:21 | -15 | 10 |
