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| 31.08.2022 | 15:00 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:2 (0:1) | |
| 01.09.2022 | 15:00 | Independiente II | - | Gimnasia de La Plata II | 4:3 (1:2) | |
| 16:00 | Arsenal de Sarandí II | - | Godoy Cruz II | 2:2 (2:0) | ||
| 16:00 | San Lorenzo II | - | Defensa y Justicia II | 1:0 (0:0) | ||
| 03.09.2022 | 15:00 | Barracas Central II | - | River Plate II | 2:1 (1:0) | |
| 16:00 | Banfield II | - | Atlético Tucumán II | 1:0 (0:0) | ||
| 16:00 | Sarmiento de Junín II | - | Aldosivi II | 0:0 (0:0) | ||
| 16:00 | Talleres de Córdoba II | - | Rosario Central II | 3:2 (2:1) | ||
| 16:00 | Central Córdoba SdE II | - | Huracán II | 1:3 (0:2) | ||
| 04.09.2022 | 15:00 | Boca Juniors II | - | Colón de Santa Fe II | 2:0 (1:0) | |
| 16:00 | Tigre II | - | Lanús II | 1:1 (0:1) | ||
| 17:00 | Unión de Santa Fe II | - | Patronato de Paraná II | 2:1 (0:0) | ||
| 05.09.2022 | 15:00 | Argentinos Juniors II | - | Racing Club II | 1:0 (0:0) | |
| 16:00 | Estudiantes II | - | Platense II | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors II | 17 | 12 | 1 | 4 | 33:11 | 22 | 37 |
| 2 |
|
Vélez Sarsfield II | 17 | 10 | 2 | 5 | 31:11 | 20 | 32 |
| 3 |
|
Argentinos Juniors II | 17 | 9 | 5 | 3 | 27:15 | 12 | 32 |
| 4 |
|
Huracán II | 17 | 9 | 3 | 5 | 34:26 | 8 | 30 |
| 5 |
|
Newell's Old Boys II | 17 | 8 | 6 | 3 | 22:15 | 7 | 30 |
| 6 |
|
Gimnasia de La Plata II | 17 | 8 | 4 | 5 | 28:21 | 7 | 28 |
| 7 |
|
River Plate II | 17 | 9 | 1 | 7 | 20:15 | 5 | 28 |
| 8 |
|
Tigre II | 17 | 7 | 5 | 5 | 19:19 | 0 | 26 |
| 9 |
|
Defensa y Justicia II | 17 | 8 | 2 | 7 | 19:21 | -2 | 26 |
| 10 |
|
Rosario Central II | 17 | 7 | 4 | 6 | 31:27 | 4 | 25 |
| 11 |
|
Independiente II | 17 | 7 | 4 | 6 | 27:24 | 3 | 25 |
| 12 |
|
Unión de Santa Fe II | 17 | 6 | 7 | 4 | 17:14 | 3 | 25 |
| 13 |
|
San Lorenzo II | 17 | 7 | 3 | 7 | 21:20 | 1 | 24 |
| 14 |
|
Lanús II | 17 | 7 | 3 | 7 | 28:30 | -2 | 24 |
| 15 |
|
Colón de Santa Fe II | 17 | 6 | 6 | 5 | 22:24 | -2 | 24 |
| 16 |
|
Banfield II | 17 | 6 | 5 | 6 | 15:16 | -1 | 23 |
| 17 |
|
Talleres de Córdoba II | 17 | 6 | 4 | 7 | 21:23 | -2 | 22 |
| 18 |
|
Central Córdoba SdE II | 17 | 6 | 4 | 7 | 17:23 | -6 | 22 |
| 19 |
|
Atlético Tucumán II | 17 | 6 | 3 | 8 | 23:24 | -1 | 21 |
| 20 |
|
Arsenal de Sarandí II | 17 | 4 | 7 | 6 | 17:19 | -2 | 19 |
| 21 |
|
Racing Club II | 17 | 4 | 6 | 7 | 23:21 | 2 | 18 |
| 22 |
|
Godoy Cruz II | 17 | 4 | 6 | 7 | 19:25 | -6 | 18 |
| 23 |
|
Platense II | 17 | 3 | 8 | 6 | 11:16 | -5 | 17 |
| 24 |
|
Estudiantes II | 17 | 3 | 8 | 6 | 11:17 | -6 | 17 |
| 25 |
|
Aldosivi II | 17 | 5 | 2 | 10 | 25:37 | -12 | 17 |
| 26 |
|
Barracas Central II | 17 | 5 | 1 | 11 | 11:30 | -19 | 16 |
| 27 |
|
Patronato de Paraná II | 17 | 4 | 3 | 10 | 13:27 | -14 | 15 |
|
Sarmiento de Junín II | 17 | 4 | 3 | 10 | 13:27 | -14 | 15 | |
