 |
 |
|
|
| 19.02.2022 | 16:15 | Cercle Brugge | - | K Beerschot VA | 2:0 (2:0) | |
| 18:30 | KV Kortrijk | - | SV Zulte Waregem | 5:0 (2:0) | ||
| 18:30 | KV Oostende | - | Standard Liège | 1:0 (1:0) | ||
| 20:45 | Sporting Charleroi | - | Union Saint-Gilloise | 0:3 (0:2) | ||
| 20.02.2022 | 13:30 | Royal Antwerp FC | - | KV Mechelen | 1:2 (0:2) | |
| 16:00 | KAS Eupen | - | Club Brugge KV | 1:3 (0:1) | ||
| 18:30 | RSC Anderlecht | - | KRC Genk | 2:0 (2:0) | ||
| 21:00 | Sint-Truidense VV | - | Oud-Heverlee Leuven | 2:0 (1:0) | ||
| 23.02.2022 | 18:45 | Gante | - | RFC Seraing | 4:0 (3:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Union Saint-Gilloise | 28 | 20 | 3 | 5 | 62:22 | 40 | 63 |
| 2 |
|
Club Brugge KV | 28 | 15 | 9 | 4 | 52:33 | 19 | 54 |
| 3 |
|
Royal Antwerp FC | 28 | 16 | 5 | 7 | 48:30 | 18 | 53 |
| 4 |
|
RSC Anderlecht | 28 | 14 | 9 | 5 | 60:32 | 28 | 51 |
| 5 |
|
Gante | 28 | 13 | 7 | 8 | 43:27 | 16 | 46 |
| 6 |
|
KV Mechelen | 28 | 14 | 3 | 11 | 48:51 | -3 | 45 |
| 7 |
|
Sporting Charleroi | 28 | 12 | 7 | 9 | 42:38 | 4 | 43 |
| 8 |
|
KRC Genk | 28 | 12 | 5 | 11 | 54:41 | 13 | 41 |
| 9 |
|
Oud-Heverlee Leuven | 28 | 10 | 9 | 9 | 44:44 | 0 | 39 |
| 10 |
|
Cercle Brugge | 28 | 11 | 5 | 12 | 40:34 | 6 | 38 |
| 11 |
|
KV Kortrijk | 28 | 9 | 10 | 9 | 37:34 | 3 | 37 |
| 12 |
|
Sint-Truidense VV | 28 | 11 | 4 | 13 | 32:37 | -5 | 37 |
| 13 |
|
Standard Liège | 28 | 8 | 8 | 12 | 30:43 | -13 | 32 |
| 14 |
|
KV Oostende | 28 | 9 | 4 | 15 | 28:52 | -24 | 31 |
| 15 |
|
KAS Eupen | 28 | 7 | 6 | 15 | 33:49 | -16 | 27 |
| 16 |
|
SV Zulte Waregem | 28 | 6 | 8 | 14 | 37:61 | -24 | 26 |
| 17 |
|
RFC Seraing | 28 | 7 | 2 | 19 | 26:57 | -31 | 23 |
| 18 |
|
K Beerschot VA | 28 | 4 | 4 | 20 | 27:58 | -31 | 16 |
| Playoff | |
| Playoff | |
| Permanencia | |
| Descenso |
