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| 06.02.2009 | 20:30 | KV Kortrijk | - | Standard Liège | 0:2 (0:0) | |
| 07.02.2009 | 20:00 | AFC Tubize | - | KV Mechelen | 1:5 (1:3) | |
| 20:00 | FCV Dender EH | - | Club Brugge KV | 0:2 (0:0) | ||
| 20:00 | KSV Roeselare | - | Germinal Beerschot | 2:2 (2:2) | ||
| 20:00 | KRC Genk | - | SV Zulte Waregem | 1:2 (0:2) | ||
| 20:00 | RSC Anderlecht | - | RAEC Mons | 3:2 (2:2) | ||
| 20:00 | Gante | - | Excelsior Mouscron | 2:0 (1:0) | ||
| 08.02.2009 | 18:00 | KVC Westerlo | - | Sporting Lokeren | 1:0 (0:0) | |
| 20:30 | Cercle Brugge | - | Sporting Charleroi | 2:2 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RSC Anderlecht | 21 | 15 | 2 | 4 | 52:23 | 29 | 47 |
| 2 |
|
Standard Liège | 21 | 14 | 4 | 3 | 39:19 | 20 | 46 |
| 3 |
|
Club Brugge KV | 21 | 12 | 4 | 5 | 38:27 | 11 | 40 |
| 4 |
|
KRC Genk | 21 | 11 | 3 | 7 | 32:29 | 3 | 36 |
| 5 |
|
KVC Westerlo | 21 | 10 | 4 | 7 | 26:24 | 2 | 34 |
| 6 |
|
Cercle Brugge | 21 | 10 | 3 | 8 | 34:33 | 1 | 33 |
| 7 |
|
Gante | 21 | 9 | 5 | 7 | 43:29 | 14 | 32 |
| 8 |
|
SV Zulte Waregem | 21 | 9 | 4 | 8 | 32:28 | 4 | 31 |
| 9 |
|
Sporting Lokeren | 21 | 7 | 9 | 5 | 26:20 | 6 | 30 |
| 10 |
|
Excelsior Mouscron | 21 | 8 | 5 | 8 | 31:29 | 2 | 29 |
| 11 |
|
KV Kortrijk | 21 | 7 | 7 | 7 | 22:30 | -8 | 28 |
| 12 |
|
Germinal Beerschot | 21 | 6 | 7 | 8 | 27:27 | 0 | 25 |
| 13 |
|
KV Mechelen | 21 | 5 | 8 | 8 | 27:35 | -8 | 23 |
| 14 |
|
Sporting Charleroi | 21 | 6 | 4 | 11 | 28:38 | -10 | 22 |
| 15 |
|
FCV Dender EH | 21 | 4 | 6 | 11 | 25:39 | -14 | 18 |
| 16 |
|
AFC Tubize | 21 | 5 | 3 | 13 | 25:46 | -21 | 18 |
| 17 |
|
RAEC Mons | 21 | 3 | 7 | 11 | 23:32 | -9 | 16 |
| 18 |
|
KSV Roeselare | 21 | 3 | 5 | 13 | 19:41 | -22 | 14 |
| CL Ronda previa | |
| Europa League | |
| Permanencia | |
| Descenso |
