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| 23.07.2022 | 01:00 | Alianza Petrolera | - | Atlético Bucaramanga | 3:1 (0:0) | |
| 03:05 | Millonarios | - | Envigado FC | 1:0 (1:0) | ||
| 21:00 | Águilas Doradas | - | La Equidad | 3:0 (2:0) | ||
| 23:05 | Deportivo Pasto | - | Unión Magdalena | 1:2 (1:1) | ||
| 24.07.2022 | 01:10 | Atlético Junior | - | Santa Fe | 2:0 (1:0) | |
| 03:15 | Deportes Tolima | - | Atlético Nacional | 2:2 (0:1) | ||
| 21:45 | América de Cali | - | Cortuluá | 1:1 (1:0) | ||
| 23:50 | Independiente Medellín | - | Once Caldas | 1:1 (1:1) | ||
| 25.07.2022 | 23:40 | Deportivo Pereira | - | Deportivo Cali | 2:1 (1:1) | |
| 26.07.2022 | 23:40 | Patriotas FC | - | Jaguares de Córdoba | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Unión Magdalena | 4 | 3 | 1 | 0 | 7:4 | 3 | 10 |
| 2 |
|
Deportivo Pereira | 4 | 3 | 0 | 1 | 6:3 | 3 | 9 |
| 3 |
|
Millonarios | 4 | 2 | 2 | 0 | 4:2 | 2 | 8 |
| 4 |
|
Deportivo Pasto | 4 | 2 | 1 | 1 | 7:3 | 4 | 7 |
| 5 |
|
Atlético Junior | 4 | 2 | 1 | 1 | 5:2 | 3 | 7 |
| 6 |
|
Alianza Petrolera | 4 | 2 | 1 | 1 | 7:5 | 2 | 7 |
| 7 |
|
Águilas Doradas | 4 | 2 | 1 | 1 | 6:4 | 2 | 7 |
| 8 |
|
Once Caldas | 4 | 1 | 3 | 0 | 6:4 | 2 | 6 |
| 9 |
|
Independiente Medellín | 4 | 1 | 3 | 0 | 5:4 | 1 | 6 |
| 10 |
|
Deportes Tolima | 4 | 1 | 2 | 1 | 6:5 | 1 | 5 |
| 11 |
|
América de Cali | 4 | 1 | 2 | 1 | 3:2 | 1 | 5 |
| 12 |
|
Jaguares de Córdoba | 4 | 1 | 2 | 1 | 3:3 | 0 | 5 |
| 13 |
|
Santa Fe | 4 | 1 | 2 | 1 | 5:6 | -1 | 5 |
| 14 |
|
Patriotas FC | 4 | 1 | 1 | 2 | 1:3 | -2 | 4 |
| 15 |
|
La Equidad | 4 | 0 | 3 | 1 | 3:6 | -3 | 3 |
| 16 |
|
Cortuluá | 4 | 0 | 2 | 2 | 2:4 | -2 | 2 |
| 17 |
|
Atlético Nacional | 4 | 0 | 2 | 2 | 5:8 | -3 | 2 |
|
Deportivo Cali | 4 | 0 | 2 | 2 | 5:8 | -3 | 2 | |
| 19 |
|
Envigado FC | 4 | 0 | 2 | 2 | 2:7 | -5 | 2 |
| 20 |
|
Atlético Bucaramanga | 4 | 0 | 1 | 3 | 1:6 | -5 | 1 |
| Próxima ronda |
