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| 20.04.2021 | 15:00 | Baník Ostrava | - | FK Mladá Boleslav | 2:1 (0:1) | |
| 15:00 | Dynamo České Budějovice | - | Sigma Olomouc | 2:2 (2:0) | ||
| 17:00 | FK Jablonec | - | MFK Karviná | 3:0 (3:0) | ||
| 21.04.2021 | 15:00 | 1. FC Slovácko | - | Zbrojovka Brno | 4:2 (2:1) | |
| 15:00 | 1. FK Příbram | - | Bohemians Praha 1905 | 1:4 (0:0) | ||
| 15:00 | FK Teplice | - | Viktoria Plzeň | 0:1 (0:0) | ||
| 15:00 | SFC Opava | - | Slovan Liberec | 0:2 (0:2) | ||
| 17:00 | FK Pardubice | - | Sparta Praga | 2:2 (0:2) | ||
| 19:30 | Slavia Praga | - | FC Fastav Zlín | 2:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praga | 28 | 23 | 5 | 0 | 75:16 | 59 | 74 |
| 2 |
|
Sparta Praga | 28 | 18 | 4 | 6 | 60:32 | 28 | 58 |
| 3 |
|
FK Jablonec | 28 | 17 | 5 | 6 | 48:29 | 19 | 56 |
| 4 |
|
1. FC Slovácko | 28 | 16 | 5 | 7 | 51:29 | 22 | 53 |
| 5 |
|
Viktoria Plzeň | 28 | 14 | 6 | 8 | 47:32 | 15 | 48 |
| 6 |
|
Slovan Liberec | 28 | 13 | 7 | 8 | 39:24 | 15 | 46 |
| 7 |
|
FK Pardubice | 28 | 12 | 6 | 10 | 31:37 | -6 | 42 |
| 8 |
|
Baník Ostrava | 28 | 11 | 8 | 9 | 39:27 | 12 | 41 |
| 9 |
|
Sigma Olomouc | 28 | 9 | 12 | 7 | 35:29 | 6 | 39 |
| 10 |
|
Bohemians Praha 1905 | 28 | 9 | 10 | 9 | 33:30 | 3 | 37 |
| 11 |
|
MFK Karviná | 28 | 8 | 9 | 11 | 31:42 | -11 | 33 |
| 12 |
|
Dynamo České Budějovice | 28 | 7 | 11 | 10 | 29:40 | -11 | 32 |
| 13 |
|
FC Fastav Zlín | 28 | 8 | 5 | 15 | 27:39 | -12 | 29 |
| 14 |
|
FK Mladá Boleslav | 28 | 6 | 9 | 13 | 35:45 | -10 | 27 |
| 15 |
|
FK Teplice | 28 | 6 | 6 | 16 | 29:58 | -29 | 24 |
| 16 |
|
Zbrojovka Brno | 28 | 4 | 8 | 16 | 24:45 | -21 | 20 |
| 17 |
|
1. FK Příbram | 28 | 3 | 8 | 17 | 19:58 | -39 | 17 |
| 18 |
|
SFC Opava | 28 | 3 | 6 | 19 | 16:56 | -40 | 15 |
| CL Ronda previa | |
| EL Ronda previa | |
| ECL Ronda previa | |
| Descenso |
