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| 13.12.2008 | 20:00 | Valencia | - | Espanyol | 2:1 (0:1) | |
| 22:00 | Barcelona | - | Real Madrid | 2:0 (0:0) | ||
| 14.12.2008 | 17:00 | Getafe | - | Mallorca | 4:1 (2:1) | |
| 17:00 | RC Recreativo | - | Osasuna | 1:0 (0:0) | ||
| 17:00 | Valladolid | - | Deportivo | 3:0 (2:0) | ||
| 17:00 | Málaga | - | Numancia | 2:0 (0:0) | ||
| 17:00 | Almería | - | Real Racing | 1:1 (0:1) | ||
| 17:00 | Athletic | - | Sporting | 3:0 (3:0) | ||
| 19:00 | Sevilla | - | Villarreal | 1:0 (1:0) | ||
| 21:00 | Atlético | - | Betis | 2:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Barcelona | 15 | 12 | 2 | 1 | 46:9 | 37 | 38 |
| 2 |
|
Valencia | 15 | 9 | 3 | 3 | 30:19 | 11 | 30 |
| 3 |
|
Sevilla | 15 | 9 | 3 | 3 | 23:14 | 9 | 30 |
| 4 |
|
Villarreal | 15 | 8 | 5 | 2 | 26:19 | 7 | 29 |
| 5 |
|
Atlético | 15 | 8 | 3 | 4 | 35:21 | 14 | 27 |
| 6 |
|
Real Madrid | 15 | 8 | 2 | 5 | 33:26 | 7 | 26 |
| 7 |
|
Deportivo | 15 | 7 | 3 | 5 | 16:17 | -1 | 24 |
| 8 |
|
Valladolid | 15 | 7 | 2 | 6 | 22:20 | 2 | 23 |
| 9 |
|
Getafe | 15 | 5 | 6 | 4 | 21:20 | 1 | 21 |
| 10 |
|
Málaga | 15 | 6 | 3 | 6 | 23:25 | -2 | 21 |
| 11 |
|
Betis | 15 | 5 | 3 | 7 | 21:21 | 0 | 18 |
| 12 |
|
Sporting | 15 | 6 | 0 | 9 | 23:35 | -12 | 18 |
| 13 |
|
Real Racing | 15 | 4 | 5 | 6 | 17:21 | -4 | 17 |
| 14 |
|
Athletic | 15 | 4 | 4 | 7 | 19:24 | -5 | 16 |
| 15 |
|
Almería | 15 | 4 | 4 | 7 | 16:24 | -8 | 16 |
| 16 |
|
Numancia | 15 | 4 | 2 | 9 | 17:30 | -13 | 14 |
| 17 |
|
Espanyol | 15 | 3 | 4 | 8 | 12:22 | -10 | 13 |
| 18 |
|
Mallorca | 15 | 3 | 4 | 8 | 17:29 | -12 | 13 |
| 19 |
|
RC Recreativo | 15 | 3 | 4 | 8 | 10:22 | -12 | 13 |
| 20 |
|
Osasuna | 15 | 1 | 6 | 8 | 11:20 | -9 | 9 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
