 |
 |
| 15.05.2022 | 12:00 | CD Coria | - | CD Mensajero | 3:2 (1:0) | |
| 12:00 | AD Ceuta FC | - | CP Cacereño | 3:0 (1:0) | ||
| 12:00 | Don Benito | - | UD San Fernando | 2:2 (2:0) | ||
| 12:00 | Cádiz CF B | - | Antequera CF | 1:0 (0:0) | ||
| 12:00 | UD Montijo | - | UD Tamaraceite | 1:7 (0:3) | ||
| 12:00 | CF Panadería Pulido | - | CF Villanovense | 1:3 (1:3) | ||
| 12:00 | Las Palmas Atlético | - | Mérida AD | 1:3 (0:1) | ||
| 12:00 | Vélez CF | - | Córdoba | 1:2 (0:1) | ||
| 12:00 | Xerez DFC | - | CD San Roque de Lepe | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Córdoba | 34 | 25 | 7 | 2 | 86:29 | 57 | 82 |
| 2 |
|
Mérida AD | 34 | 18 | 8 | 8 | 49:26 | 23 | 62 |
| 3 |
|
CP Cacereño | 34 | 17 | 10 | 7 | 48:37 | 11 | 61 |
| 4 |
|
AD Ceuta FC | 34 | 14 | 12 | 8 | 46:32 | 14 | 54 |
| 5 |
|
CD Coria | 34 | 15 | 8 | 11 | 42:40 | 2 | 53 |
| 6 |
|
CD San Roque de Lepe | 34 | 14 | 10 | 10 | 39:28 | 11 | 52 |
| 7 |
|
Cádiz CF B | 34 | 13 | 11 | 10 | 36:35 | 1 | 50 |
| 8 |
|
CF Villanovense | 34 | 14 | 8 | 12 | 39:28 | 11 | 50 |
| 9 |
|
UD Montijo | 34 | 13 | 8 | 13 | 37:38 | -1 | 47 |
| 10 |
|
Xerez DFC | 34 | 13 | 8 | 13 | 28:40 | -12 | 47 |
| 11 |
|
Vélez CF | 34 | 13 | 7 | 14 | 39:42 | -3 | 46 |
| 12 |
|
Antequera CF | 34 | 11 | 11 | 12 | 36:37 | -1 | 44 |
| 13 |
|
Don Benito | 34 | 10 | 11 | 13 | 43:42 | 1 | 41 |
| 14 |
|
CD Mensajero | 34 | 7 | 14 | 13 | 35:47 | -12 | 35 |
| 15 |
|
Las Palmas Atlético | 34 | 7 | 10 | 17 | 41:61 | -20 | 31 |
| 16 |
|
UD San Fernando | 34 | 7 | 8 | 19 | 30:55 | -25 | 29 |
| 17 |
|
CF Panadería Pulido | 34 | 5 | 10 | 19 | 32:61 | -29 | 25 |
| 18 |
|
UD Tamaraceite | 34 | 6 | 7 | 21 | 36:64 | -28 | 25 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
