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| 11.09.2022 | 11:30 | Juventud Torremolinos | - | Utrera CD | 0:0 (0:0) | |
| 12:00 | Betis B | - | Mar Menor CF | 0:1 (0:0) | ||
| 12:00 | Cádiz CF B | - | Granada B | 1:2 (1:1) | ||
| 12:00 | Atlético Sanluqueño CF | - | FC Cartagena B | 1:0 (1:0) | ||
| 18:00 | CD San Roque de Lepe | - | RC Recreativo | 0:1 (0:1) | ||
| 18:00 | Yeclano Deportivo | - | Sevilla Atlético | 2:1 (1:0) | ||
| 19:00 | Antequera CF | - | CD El Ejido 2012 | 2:0 (0:0) | ||
| 19:00 | Atlético Mancha Real | - | Vélez CF | 1:1 (0:0) | ||
| 19:30 | UCAM Murcia CF | - | Xerez DFC | 3:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 2 | 2 | 0 | 0 | 5:2 | 3 | 6 |
| 2 |
|
RC Recreativo | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 3 |
|
Mar Menor CF | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 4 |
|
Granada B | 2 | 1 | 1 | 0 | 3:2 | 1 | 4 |
| 5 |
|
Atlético Mancha Real | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 |
|
Atlético Sanluqueño CF | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
| 7 |
|
UCAM Murcia CF | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 8 |
|
Yeclano Deportivo | 2 | 1 | 0 | 1 | 3:3 | 0 | 3 |
| 9 |
|
Betis B | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 |
| 10 |
|
Sevilla Atlético | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 11 |
|
Cádiz CF B | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 12 |
|
Vélez CF | 2 | 0 | 2 | 0 | 3:3 | 0 | 2 |
| 13 |
|
Juventud Torremolinos | 2 | 0 | 2 | 0 | 2:2 | 0 | 2 |
| 14 |
|
Utrera CD | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
| 15 |
|
CD San Roque de Lepe | 2 | 0 | 0 | 2 | 1:3 | -2 | 0 |
| 16 |
|
CD El Ejido 2012 | 2 | 0 | 0 | 2 | 0:4 | -4 | 0 |
|
Xerez DFC | 2 | 0 | 0 | 2 | 0:4 | -4 | 0 | |
| 18 |
|
FC Cartagena B | 2 | 0 | 0 | 2 | 0:2 | -2 | 0 |
| Ascenso | |
| Playoff | |
| Descenso |
