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| 23.07.2022 | 16:00 | CF Pachuca | - | Club Necaxa | 1:2 (0:2) | |
| 18:00 | Puebla FC | - | Cruz Azul | 2:1 (1:0) | ||
| 18:00 | UANL Tigres | - | CF Monterrey | 1:1 (1:1) | ||
| 18:30 | Atlas Guadalajara | - | Atlético San Luis | 8:1 (5:0) | ||
| 18:30 | Santos Laguna | - | Mazatlán FC | 5:0 (4:0) | ||
| 18:30 | Club León | - | Club Tijuana | 0:1 (0:0) | ||
| 19:15 | FC Juárez | - | Deportivo Toluca | 2:3 (2:1) | ||
| 24.07.2022 | 18:00 | CF América | - | Gallos Blancos | 2:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 4 | 3 | 1 | 0 | 9:6 | 3 | 10 |
| 2 |
|
Deportivo Toluca | 4 | 2 | 2 | 0 | 8:5 | 3 | 8 |
| 3 |
|
CF Pachuca | 5 | 2 | 2 | 1 | 6:3 | 3 | 8 |
| 4 |
|
Puebla FC | 4 | 2 | 0 | 2 | 9:8 | 1 | 6 |
| 5 |
|
Club Necaxa | 4 | 2 | 0 | 2 | 5:4 | 1 | 6 |
| 6 |
|
Cruz Azul | 5 | 2 | 0 | 3 | 11:12 | -1 | 6 |
| 7 |
|
Gallos Blancos | 5 | 1 | 2 | 2 | 7:7 | 0 | 5 |
| 8 |
|
CF América | 4 | 1 | 1 | 2 | 8:10 | -2 | 4 |
| 9 |
|
FC Juárez | 5 | 1 | 0 | 4 | 7:15 | -8 | 3 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Tijuana | 5 | 4 | 1 | 0 | 14:2 | 12 | 13 |
| 2 |
|
Atlas Guadalajara | 5 | 3 | 2 | 0 | 14:3 | 11 | 11 |
| 3 |
|
CF Monterrey | 5 | 3 | 2 | 0 | 16:6 | 10 | 11 |
| 4 |
|
Deportivo Guadalajara | 4 | 3 | 0 | 1 | 5:4 | 1 | 9 |
| 5 |
|
Santos Laguna | 5 | 2 | 0 | 3 | 15:10 | 5 | 6 |
| 6 |
|
Club León | 4 | 1 | 0 | 3 | 4:5 | -1 | 3 |
| 7 |
|
Atlético San Luis | 4 | 1 | 0 | 3 | 5:21 | -16 | 3 |
| 8 |
|
UANL Tigres | 4 | 0 | 1 | 3 | 3:13 | -10 | 1 |
| 9 |
|
Mazatlán FC | 4 | 0 | 0 | 4 | 2:14 | -12 | 0 |
| Playoff | |
| Playoff |
