 |
 |
|
|
| 11.03.2022 | 18:15 | Club Necaxa | - | Gallos Blancos | 2:0 (1:0) | |
| 18:30 | CF Monterrey | - | Mazatlán FC | 2:2 (1:0) | ||
| 19:00 | Cruz Azul | - | Pumas UNAM | 0:2 (0:0) | ||
| 22:30 | FC Juárez | - | Atlas Guadalajara | 0:3 (0:3) | ||
| 12.03.2022 | 16:00 | Santos Laguna | - | Club Tijuana | 4:0 (1:0) | |
| 18:15 | Deportivo Guadalajara | - | CF América | 3:2 (1:2) | ||
| 18:30 | Club León | - | UANL Tigres | 2:1 (1:0) | ||
| 13.03.2022 | 18:30 | Deportivo Toluca | - | CF Pachuca | 0:2 (0:1) | |
| 18:30 | Atlético San Luis | - | Puebla FC | 1:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlas Guadalajara | 10 | 7 | 3 | 0 | 18:7 | 11 | 35 |
| 2 |
|
CF América | 10 | 7 | 2 | 1 | 21:9 | 12 | 33 |
| 3 |
|
Club León | 10 | 7 | 1 | 2 | 14:8 | 6 | 29 |
| 4 |
|
Deportivo Guadalajara | 10 | 6 | 2 | 2 | 21:12 | 9 | 28 |
| 5 |
|
Club Tijuana | 10 | 4 | 3 | 3 | 17:17 | 0 | 26 |
| 6 |
|
Santos Laguna | 10 | 4 | 4 | 2 | 19:10 | 9 | 25 |
| 7 |
|
CF Monterrey | 10 | 4 | 2 | 4 | 18:21 | -3 | 25 |
| 8 |
|
Deportivo Toluca | 10 | 4 | 4 | 2 | 14:10 | 4 | 24 |
| 9 |
|
CF Pachuca | 10 | 5 | 0 | 5 | 17:14 | 3 | 22 |
| 10 |
|
Cruz Azul | 10 | 4 | 1 | 5 | 10:12 | -2 | 22 |
| 11 |
|
Pumas UNAM | 10 | 4 | 2 | 4 | 12:12 | 0 | 21 |
| 12 |
|
UANL Tigres | 10 | 3 | 2 | 5 | 13:21 | -8 | 20 |
| 13 |
|
Atlético San Luis | 10 | 4 | 1 | 5 | 14:15 | -1 | 19 |
| 14 |
|
Mazatlán FC | 10 | 2 | 3 | 5 | 10:20 | -10 | 19 |
| 15 |
|
Club Necaxa | 10 | 3 | 0 | 7 | 13:19 | -6 | 16 |
| 16 |
|
FC Juárez | 10 | 1 | 4 | 5 | 11:16 | -5 | 14 |
| 17 |
|
Gallos Blancos | 10 | 2 | 0 | 8 | 6:15 | -9 | 13 |
| 18 |
|
Puebla FC | 10 | 0 | 4 | 6 | 4:14 | -10 | 13 |
| Playoff |
