 |
 |
|
|
| 17.03.2022 | 16:00 | Gallos Blancos | - | Atlético San Luis | 3:0 (1:0) | |
| 18.03.2022 | 16:00 | Puebla FC | - | Santos Laguna | 0:1 (0:0) | |
| 23:45 | Club Tijuana | - | FC Juárez | 1:1 (0:0) | ||
| 19.03.2022 | 16:00 | UANL Tigres | - | CF Monterrey | 0:1 (0:1) | |
| 16:00 | Pumas UNAM | - | Club Necaxa | 1:2 (1:0) | ||
| 19:00 | CF Pachuca | - | Cruz Azul | 1:0 (0:0) | ||
| 20.03.2022 | 16:00 | CF América | - | Deportivo Toluca | 2:0 (0:0) | |
| 16:00 | Atlas Guadalajara | - | Deportivo Guadalajara | 1:2 (1:1) | ||
| 17:00 | Mazatlán FC | - | Club León | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 11 | 8 | 1 | 2 | 22:12 | 10 | 25 |
| 2 |
|
Club León | 11 | 7 | 1 | 3 | 20:12 | 8 | 22 |
| 3 |
|
Club Tijuana | 11 | 6 | 2 | 3 | 17:14 | 3 | 20 |
| 4 |
|
Deportivo Guadalajara | 11 | 6 | 2 | 3 | 12:11 | 1 | 20 |
| 5 |
|
Atlético San Luis | 11 | 6 | 1 | 4 | 25:16 | 9 | 19 |
| 6 |
|
CF América | 11 | 6 | 1 | 4 | 19:10 | 9 | 19 |
| 7 |
|
Deportivo Toluca | 11 | 5 | 3 | 3 | 17:14 | 3 | 18 |
| 8 |
|
UANL Tigres | 11 | 5 | 2 | 4 | 19:13 | 6 | 17 |
| 9 |
|
Santos Laguna | 11 | 5 | 2 | 4 | 14:16 | -2 | 17 |
| 10 |
|
Club Necaxa | 11 | 5 | 1 | 5 | 17:16 | 1 | 16 |
| 11 |
|
Pumas UNAM | 11 | 4 | 3 | 4 | 12:10 | 2 | 15 |
| 12 |
|
CF Monterrey | 11 | 4 | 3 | 4 | 13:18 | -5 | 15 |
| 13 |
|
Cruz Azul | 11 | 3 | 4 | 4 | 11:10 | 1 | 13 |
| 14 |
|
Mazatlán FC | 11 | 4 | 1 | 6 | 12:18 | -6 | 13 |
| 15 |
|
Atlas Guadalajara | 11 | 2 | 3 | 6 | 8:16 | -8 | 9 |
| 16 |
|
Puebla FC | 11 | 2 | 1 | 8 | 11:24 | -13 | 7 |
| 17 |
|
FC Juárez | 11 | 1 | 4 | 6 | 9:22 | -13 | 7 |
| 18 |
|
Gallos Blancos | 11 | 1 | 3 | 7 | 5:11 | -6 | 6 |
| Playoff |
