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| 28.08.2010 | 17:00 | FK Skopje | - | FK Turnovo | 3:0 (1:0) | |
| 17:00 | Napredok Kičevo | - | FK Renova | 1:0 (1:0) | ||
| 17:00 | FK Teteks | - | Metalurg Skopje | 0:0 (0:0) | ||
| 17:00 | FK Bregalnica Štip | - | FK Rabotnički | 0:2 (0:0) | ||
| 20:00 | Vardar Skopje | - | FK Pelister | 1:0 (0:0) | ||
| 29.08.2010 | 17:00 | KF Shkëndija 79 | - | Sileks Kratovo | 3:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Metalurg Skopje | 5 | 3 | 2 | 0 | 7:2 | 5 | 11 |
| 2 |
|
FK Turnovo | 5 | 3 | 1 | 1 | 10:3 | 7 | 10 |
| 3 |
|
FK Teteks | 5 | 2 | 3 | 0 | 5:2 | 3 | 9 |
| 4 |
|
KF Shkëndija 79 | 5 | 2 | 2 | 1 | 8:3 | 5 | 8 |
| 5 |
|
FK Renova | 5 | 2 | 2 | 1 | 5:2 | 3 | 8 |
| 6 |
|
Napredok Kičevo | 5 | 2 | 2 | 1 | 3:2 | 1 | 8 |
| 7 |
|
FK Skopje | 5 | 2 | 1 | 2 | 6:6 | 0 | 7 |
| 8 |
|
FK Rabotnički | 5 | 2 | 1 | 2 | 4:5 | -1 | 7 |
| 9 |
|
FK Pelister | 5 | 1 | 1 | 3 | 3:7 | -4 | 4 |
| 10 |
|
Sileks Kratovo | 5 | 1 | 1 | 3 | 3:10 | -7 | 4 |
| 11 |
|
FK Bregalnica Štip | 5 | 1 | 0 | 4 | 2:8 | -6 | 3 |
| 12 |
|
Vardar Skopje | 5 | 1 | 0 | 4 | 2:8 | -6 | 0 |
| CL Ronda previa | |
| Europa League | |
| Permanencia | |
| Descenso |
