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| 10.10.2021 | 15:00 | 1. FC Düren | - | Fortuna Köln II | 4:0 (2:0) | |
| 15:00 | BC Viktoria Glesch-Paffendorf | - | Borussia Freialdenhoven | 1:1 (0:1) | ||
| 15:00 | Spvg Wesseling-Urfeld | - | SV Bergisch Gladbach 09 | 0:3 (0:1) | ||
| 15:00 | Viktoria Arnoldsweiler | - | VfL 08 Vichttal | 2:0 (1:0) | ||
| 15:00 | VfL Alfter | - | FC Hürth | 3:2 (1:0) | ||
| 15:00 | SV Breinig | - | Blau-Weiß Friesdorf | 2:3 (2:0) | ||
| 15:30 | FC Pesch 1956 | - | SpVg Frechen 20 | 0:0 (0:0) | ||
| 15:30 | SV Deutz 05 | - | FC Hennef 05 | 0:4 (0:2) | ||
| 15:30 | Siegburger SV 04 | - | SV 1914 Eilendorf | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 10 | 8 | 2 | 0 | 34:6 | 28 | 26 |
| 2 |
|
FC Hennef 05 | 10 | 8 | 2 | 0 | 27:4 | 23 | 26 |
| 3 |
|
SpVg Frechen 20 | 10 | 7 | 1 | 2 | 24:8 | 16 | 22 |
| 4 |
|
Borussia Freialdenhoven | 10 | 7 | 1 | 2 | 20:10 | 10 | 22 |
| 5 |
|
SV Bergisch Gladbach 09 | 10 | 5 | 4 | 1 | 23:7 | 16 | 19 |
| 6 |
|
VfL Alfter | 10 | 5 | 2 | 3 | 17:17 | 0 | 17 |
| 7 |
|
Viktoria Arnoldsweiler | 10 | 5 | 1 | 4 | 20:16 | 4 | 16 |
| 8 |
|
Siegburger SV 04 | 10 | 4 | 4 | 2 | 12:9 | 3 | 16 |
| 9 |
|
FC Hürth | 10 | 5 | 1 | 4 | 15:18 | -3 | 16 |
| 10 |
|
FC Pesch 1956 | 10 | 3 | 5 | 2 | 20:10 | 10 | 14 |
| 11 |
|
BC Viktoria Glesch-Paffendorf | 10 | 4 | 2 | 4 | 14:13 | 1 | 14 |
| 12 |
|
VfL 08 Vichttal | 10 | 4 | 2 | 4 | 16:20 | -4 | 14 |
| 13 |
|
Blau-Weiß Friesdorf | 10 | 3 | 3 | 4 | 14:17 | -3 | 12 |
| 14 |
|
SV Deutz 05 | 10 | 2 | 2 | 6 | 10:25 | -15 | 8 |
| 15 |
|
Fortuna Köln II | 10 | 1 | 2 | 7 | 8:22 | -14 | 5 |
| 16 |
|
SV 1914 Eilendorf | 10 | 1 | 0 | 9 | 4:26 | -22 | 3 |
| 17 |
|
Spvg Wesseling-Urfeld | 10 | 1 | 0 | 9 | 8:34 | -26 | 3 |
| 18 |
|
SV Breinig | 10 | 0 | 0 | 10 | 5:29 | -24 | 0 |
| Playoff | |
| Descenso |
