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| 17.09.2021 | 02:00 | Independiente de La Chorrera | - | Sporting San Miguelito | 3:0 (0:0) | |
| 18.09.2021 | 02:00 | Herrera FC | - | Deportivo del Este | 1:1 (1:0) | |
| 23:00 | Árabe Unido | - | Veraguas Club Deportivo | 0:0 (0:0) | ||
| 19.09.2021 | 01:00 | Plaza Amador | - | San Francisco FC | 1:1 (0:1) | |
| 01:00 | Atlético Chiriquí | - | Tauro FC | 0:1 (0:0) | ||
| 02:00 | Alianza | - | UD Universitario | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tauro FC | 7 | 4 | 2 | 1 | 7:3 | 4 | 14 |
| 2 |
|
Alianza | 7 | 4 | 2 | 1 | 8:5 | 3 | 14 |
| 3 |
|
Sporting San Miguelito | 7 | 3 | 2 | 2 | 5:6 | -1 | 11 |
| 4 |
|
Árabe Unido | 7 | 2 | 3 | 2 | 4:4 | 0 | 9 |
| 5 |
|
Deportivo del Este | 7 | 0 | 6 | 1 | 6:7 | -1 | 6 |
| 6 |
|
Plaza Amador | 7 | 0 | 5 | 2 | 3:5 | -2 | 5 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente de La Chorrera | 7 | 4 | 1 | 2 | 12:7 | 5 | 13 |
| 2 |
|
Herrera FC | 7 | 2 | 4 | 1 | 10:7 | 3 | 10 |
| 3 |
|
UD Universitario | 7 | 3 | 1 | 3 | 7:8 | -1 | 10 |
| 4 |
|
Atlético Chiriquí | 7 | 2 | 3 | 2 | 7:6 | 1 | 9 |
| 5 |
|
Veraguas Club Deportivo | 7 | 1 | 3 | 3 | 4:7 | -3 | 6 |
| 6 |
|
San Francisco FC | 7 | 0 | 2 | 5 | 4:12 | -8 | 2 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
