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| 26.09.2021 | 01:00 | Independiente de La Chorrera | - | Alianza | 0:0 (0:0) | |
| 01:00 | Tauro FC | - | Herrera FC | 1:1 (1:0) | ||
| 01:00 | Veraguas Club Deportivo | - | Sporting San Miguelito | 2:0 (0:0) | ||
| 27.09.2021 | 00:00 | Atlético Chiriquí | - | Árabe Unido | 0:1 (0:0) | |
| 00:00 | Deportivo del Este | - | San Francisco FC | 0:0 (0:0) | ||
| 07.10.2021 | 01:00 | UD Universitario | - | Plaza Amador | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tauro FC | 8 | 4 | 3 | 1 | 8:4 | 4 | 15 |
| 2 |
|
Alianza | 8 | 4 | 3 | 1 | 8:5 | 3 | 15 |
| 3 |
|
Árabe Unido | 8 | 3 | 3 | 2 | 5:4 | 1 | 12 |
| 4 |
|
Sporting San Miguelito | 8 | 3 | 2 | 3 | 5:8 | -3 | 11 |
| 5 |
|
Plaza Amador | 8 | 1 | 5 | 2 | 4:5 | -1 | 8 |
| 6 |
|
Deportivo del Este | 8 | 0 | 7 | 1 | 6:7 | -1 | 7 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente de La Chorrera | 8 | 4 | 2 | 2 | 12:7 | 5 | 14 |
| 2 |
|
Herrera FC | 8 | 2 | 5 | 1 | 11:8 | 3 | 11 |
| 3 |
|
UD Universitario | 8 | 3 | 1 | 4 | 7:9 | -2 | 10 |
| 4 |
|
Atlético Chiriquí | 8 | 2 | 3 | 3 | 7:7 | 0 | 9 |
| 5 |
|
Veraguas Club Deportivo | 8 | 2 | 3 | 3 | 6:7 | -1 | 9 |
| 6 |
|
San Francisco FC | 8 | 0 | 3 | 5 | 4:12 | -8 | 3 |
| Playoff | |
| Playoff | |
| Playoff | |
| Playoff |
