 |
 |
|
|
| 26.02.2021 | 23:30 | Sportivo Luqueño | - | 12 de Octubre de Itauguá | 1:0 (0:0) | |
| 27.02.2021 | 23:30 | Sol de América | - | Guaraní | 1:3 (1:1) | |
| 28.02.2021 | 22:30 | Club Olimpia | - | Cerro Porteño | 2:0 (1:0) | |
| 01.03.2021 | 22:30 | Guaireña FC | - | Club Nacional | 1:0 (0:0) | |
| 02.03.2021 | 00:45 | Libertad | - | River Plate | 2:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 5 | 4 | 0 | 1 | 8:3 | 5 | 12 |
| 2 |
|
Club Olimpia | 5 | 3 | 1 | 1 | 7:1 | 6 | 10 |
| 3 |
|
Guaraní | 5 | 3 | 1 | 1 | 11:8 | 3 | 10 |
| 4 |
|
Guaireña FC | 5 | 2 | 2 | 1 | 5:5 | 0 | 8 |
| 5 |
|
Cerro Porteño | 5 | 2 | 1 | 2 | 7:7 | 0 | 7 |
| 6 |
|
Club Nacional | 5 | 2 | 1 | 2 | 6:6 | 0 | 7 |
| 7 |
|
Sportivo Luqueño | 5 | 2 | 0 | 3 | 4:6 | -2 | 6 |
| 8 |
|
River Plate | 5 | 1 | 2 | 2 | 6:9 | -3 | 5 |
| 9 |
|
Sol de América | 5 | 1 | 1 | 3 | 8:8 | 0 | 4 |
| 10 |
|
12 de Octubre de Itauguá | 5 | 0 | 1 | 4 | 3:12 | -9 | 1 |
| Copa Libertadores |
