 |
 |
|
|
| 02.10.2021 | 01:30 | Club Olimpia | - | 12 de Octubre de Itauguá | 1:2 (1:1) | |
| 03.10.2021 | 00:00 | Sportivo Luqueño | - | Sol de América | 3:3 (3:0) | |
| 02:15 | River Plate | - | Guaireña FC | 1:1 (0:1) | ||
| 23:00 | Guaraní | - | Club Nacional | 1:1 (1:0) | ||
| 04.10.2021 | 01:15 | Libertad | - | Cerro Porteño | 0:2 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Guaraní | 11 | 6 | 4 | 1 | 27:10 | 17 | 22 |
| 2 |
|
Cerro Porteño | 11 | 5 | 4 | 2 | 11:5 | 6 | 19 |
| 3 |
|
Sportivo Luqueño | 11 | 5 | 2 | 4 | 13:18 | -5 | 17 |
| 4 |
|
Sol de América | 11 | 4 | 4 | 3 | 13:14 | -1 | 16 |
| 5 |
|
River Plate | 11 | 4 | 3 | 4 | 13:14 | -1 | 15 |
| 6 |
|
Club Nacional | 11 | 3 | 5 | 3 | 12:12 | 0 | 14 |
| 7 |
|
12 de Octubre de Itauguá | 11 | 3 | 4 | 4 | 14:18 | -4 | 13 |
| 8 |
|
Guaireña FC | 11 | 3 | 3 | 5 | 10:13 | -3 | 12 |
| 9 |
|
Libertad | 11 | 2 | 5 | 4 | 14:15 | -1 | 11 |
| 10 |
|
Club Olimpia | 11 | 3 | 0 | 8 | 12:20 | -8 | 9 |
| 11 |
|
Deportivo Recoleta | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Copa Libertadores |
