 |
 |
|
|
| 17.10.2021 | 00:30 | Club Nacional | - | Sportivo Luqueño | 0:0 (0:0) | |
| 23:00 | Sol de América | - | Libertad | 0:4 (0:1) | ||
| 18.10.2021 | 01:15 | Guaireña FC | - | Club Olimpia | 0:2 (0:1) | |
| 23:15 | 12 de Octubre de Itauguá | - | Guaraní | 1:2 (1:1) | ||
| 19.10.2021 | 01:30 | Cerro Porteño | - | River Plate | 2:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Guaraní | 12 | 7 | 4 | 1 | 29:11 | 18 | 25 |
| 2 |
|
Cerro Porteño | 12 | 6 | 4 | 2 | 13:5 | 8 | 22 |
| 3 |
|
Sportivo Luqueño | 12 | 5 | 3 | 4 | 13:18 | -5 | 18 |
| 4 |
|
Sol de América | 12 | 4 | 4 | 4 | 13:18 | -5 | 16 |
| 5 |
|
Club Nacional | 12 | 3 | 6 | 3 | 12:12 | 0 | 15 |
| 6 |
|
River Plate | 12 | 4 | 3 | 5 | 13:16 | -3 | 15 |
| 7 |
|
Libertad | 12 | 3 | 5 | 4 | 18:15 | 3 | 14 |
| 8 |
|
12 de Octubre de Itauguá | 12 | 3 | 4 | 5 | 15:20 | -5 | 13 |
| 9 |
|
Guaireña FC | 12 | 3 | 3 | 6 | 10:15 | -5 | 12 |
| 10 |
|
Club Olimpia | 12 | 4 | 0 | 8 | 14:20 | -6 | 12 |
| 11 |
|
Deportivo Recoleta | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Copa Libertadores |
