 |
 |
|
|
| 25.06.2022 | 23:00 | General Caballero DJLM | - | Resistencia SC | 2:1 (0:0) | |
| 26.06.2022 | 01:15 | Libertad | - | Cerro Porteño | 1:0 (0:0) | |
| 22:30 | Club Olimpia | - | 12 de Octubre de Itauguá | 4:1 (3:0) | ||
| 27.06.2022 | 00:45 | Club Nacional | - | Guaraní | 0:1 (0:0) | |
| 23:00 | Sportivo Ameliano | - | Guaireña FC | 2:2 (1:2) | ||
| 28.06.2022 | 01:15 | Tacuary | - | Sol de América | 2:2 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 21 | 17 | 3 | 1 | 45:14 | 31 | 54 |
| 2 |
|
Cerro Porteño | 21 | 15 | 2 | 4 | 37:13 | 24 | 47 |
| 3 |
|
Club Olimpia | 21 | 12 | 4 | 5 | 39:23 | 16 | 40 |
| 4 |
|
Guaraní | 21 | 9 | 5 | 7 | 30:22 | 8 | 32 |
| 5 |
|
Resistencia SC | 21 | 7 | 7 | 7 | 30:32 | -2 | 28 |
| 6 |
|
Club Nacional | 21 | 7 | 4 | 10 | 26:31 | -5 | 25 |
| 7 |
|
Sol de América | 21 | 6 | 7 | 8 | 20:27 | -7 | 25 |
| 8 |
|
Guaireña FC | 21 | 5 | 7 | 9 | 20:25 | -5 | 22 |
| 9 |
|
Tacuary | 21 | 6 | 4 | 11 | 16:28 | -12 | 22 |
| 10 |
|
General Caballero DJLM | 21 | 5 | 5 | 11 | 20:32 | -12 | 20 |
| 11 |
|
12 de Octubre de Itauguá | 21 | 3 | 8 | 10 | 15:37 | -22 | 17 |
| 12 |
|
Sportivo Ameliano | 21 | 4 | 4 | 13 | 24:38 | -14 | 16 |
| Copa Libertadores |
