 |
 |
|
|
| 02.04.2022 | 00:00 | Cerro Porteño | - | 12 de Octubre de Itauguá | 2:0 (0:0) | |
| 02:15 | Resistencia SC | - | Club Olimpia | 2:1 (2:0) | ||
| 03.04.2022 | 00:00 | Guaireña FC | - | Libertad | 2:3 (1:1) | |
| 02:15 | Sol de América | - | General Caballero DJLM | 2:3 (1:2) | ||
| 04.04.2022 | 00:00 | Club Nacional | - | Sportivo Ameliano | 2:1 (1:0) | |
| 02:15 | Guaraní | - | Tacuary | 1:2 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 8 | 7 | 1 | 0 | 20:5 | 15 | 22 |
| 2 |
|
Cerro Porteño | 8 | 7 | 0 | 1 | 19:6 | 13 | 21 |
| 3 |
|
Resistencia SC | 8 | 4 | 3 | 1 | 16:12 | 4 | 15 |
| 4 |
|
Club Olimpia | 8 | 4 | 2 | 2 | 13:9 | 4 | 14 |
| 5 |
|
Sol de América | 8 | 3 | 2 | 3 | 6:9 | -3 | 11 |
| 6 |
|
Tacuary | 8 | 3 | 1 | 4 | 7:9 | -2 | 10 |
| 7 |
|
Guaraní | 8 | 2 | 2 | 4 | 10:12 | -2 | 8 |
| 8 |
|
Club Nacional | 8 | 2 | 2 | 4 | 10:15 | -5 | 8 |
| 9 |
|
General Caballero DJLM | 8 | 2 | 1 | 5 | 9:12 | -3 | 7 |
| 10 |
|
Guaireña FC | 8 | 1 | 3 | 4 | 6:11 | -5 | 6 |
| 11 |
|
Sportivo Ameliano | 8 | 2 | 0 | 6 | 8:15 | -7 | 6 |
| 12 |
|
12 de Octubre de Itauguá | 8 | 1 | 3 | 4 | 7:16 | -9 | 6 |
| Copa Libertadores |
