 |
 |
|
|
| 09.04.2022 | 00:00 | 12 de Octubre de Itauguá | - | Resistencia SC | 1:1 (0:1) | |
| 02:15 | Club Olimpia | - | Club Nacional | 1:2 (1:0) | ||
| 10.04.2022 | 00:00 | General Caballero DJLM | - | Cerro Porteño | 0:0 (0:0) | |
| 02:15 | Sportivo Ameliano | - | Guaraní | 0:1 (0:1) | ||
| 11.04.2022 | 00:00 | Libertad | - | Sol de América | 3:1 (2:1) | |
| 02:15 | Tacuary | - | Guaireña FC | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 9 | 8 | 1 | 0 | 23:6 | 17 | 25 |
| 2 |
|
Cerro Porteño | 9 | 7 | 1 | 1 | 19:6 | 13 | 22 |
| 3 |
|
Resistencia SC | 9 | 4 | 4 | 1 | 17:13 | 4 | 16 |
| 4 |
|
Club Olimpia | 9 | 4 | 2 | 3 | 14:11 | 3 | 14 |
| 5 |
|
Guaraní | 9 | 3 | 2 | 4 | 11:12 | -1 | 11 |
| 6 |
|
Club Nacional | 9 | 3 | 2 | 4 | 12:16 | -4 | 11 |
| 7 |
|
Sol de América | 9 | 3 | 2 | 4 | 7:12 | -5 | 11 |
| 8 |
|
Tacuary | 9 | 3 | 1 | 5 | 7:10 | -3 | 10 |
| 9 |
|
Guaireña FC | 9 | 2 | 3 | 4 | 7:11 | -4 | 9 |
| 10 |
|
General Caballero DJLM | 9 | 2 | 2 | 5 | 9:12 | -3 | 8 |
| 11 |
|
12 de Octubre de Itauguá | 9 | 1 | 4 | 4 | 8:17 | -9 | 7 |
| 12 |
|
Sportivo Ameliano | 9 | 2 | 0 | 7 | 8:16 | -8 | 6 |
| Copa Libertadores |
