 |
 |
|
|
| 14.09.2022 | 22:45 | Libertad | - | Tacuary | 2:0 (2:0) | |
| 15.09.2022 | 01:15 | Cerro Porteño | - | Guaireña FC | 2:2 (1:0) | |
| 22:45 | Guaraní | - | Sportivo Ameliano | 2:1 (0:0) | ||
| 16.09.2022 | 01:15 | Club Nacional | - | Club Olimpia | 1:1 (0:0) | |
| 22:45 | 12 de Octubre de Itauguá | - | Resistencia SC | 1:0 (0:0) | ||
| 17.09.2022 | 01:15 | Sol de América | - | General Caballero DJLM | 3:2 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Nacional | 11 | 6 | 4 | 1 | 16:9 | 7 | 22 |
| 2 |
|
Cerro Porteño | 11 | 6 | 4 | 1 | 14:7 | 7 | 22 |
| 3 |
|
Club Olimpia | 11 | 6 | 3 | 2 | 20:12 | 8 | 21 |
| 4 |
|
Libertad | 11 | 6 | 1 | 4 | 23:16 | 7 | 19 |
| 5 |
|
Tacuary | 11 | 5 | 2 | 4 | 12:8 | 4 | 17 |
| 6 |
|
Guaireña FC | 11 | 4 | 3 | 4 | 18:16 | 2 | 15 |
| 7 |
|
Sol de América | 11 | 4 | 2 | 5 | 12:17 | -5 | 14 |
| 8 |
|
Sportivo Ameliano | 11 | 4 | 1 | 6 | 13:14 | -1 | 13 |
| 9 |
|
Guaraní | 11 | 2 | 5 | 4 | 10:14 | -4 | 11 |
| 10 |
|
Resistencia SC | 11 | 2 | 5 | 4 | 8:14 | -6 | 11 |
| 11 |
|
General Caballero DJLM | 11 | 3 | 2 | 6 | 12:20 | -8 | 11 |
| 12 |
|
12 de Octubre de Itauguá | 11 | 2 | 0 | 9 | 8:19 | -11 | 6 |
| Copa Libertadores |
