 |
 |
|
|
| 06.11.2022 | 21:00 | Libertad | - | Guaireña FC | 4:2 (3:1) | |
| 23:30 | Guaraní | - | Tacuary | 2:1 (2:0) | ||
| 07.11.2022 | 23:30 | Cerro Porteño | - | Resistencia SC | 1:0 (0:0) | |
| 08.11.2022 | 23:30 | 12 de Octubre de Itauguá | - | General Caballero DJLM | 0:3 (0:2) | |
| 23:30 | Sol de América | - | Club Olimpia | 0:2 (0:2) | ||
| 23:30 | Club Nacional | - | Sportivo Ameliano | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Olimpia | 21 | 15 | 3 | 3 | 41:18 | 23 | 48 |
| 2 |
|
Cerro Porteño | 21 | 13 | 6 | 2 | 29:12 | 17 | 45 |
| 3 |
|
Club Nacional | 21 | 13 | 5 | 3 | 29:15 | 14 | 44 |
| 4 |
|
Libertad | 21 | 10 | 4 | 7 | 35:26 | 9 | 34 |
| 5 |
|
Tacuary | 21 | 8 | 4 | 9 | 26:25 | 1 | 28 |
| 6 |
|
General Caballero DJLM | 21 | 8 | 3 | 10 | 26:26 | 0 | 27 |
| 7 |
|
Guaireña FC | 21 | 7 | 6 | 8 | 25:28 | -3 | 27 |
| 8 |
|
Sportivo Ameliano | 21 | 8 | 2 | 11 | 25:30 | -5 | 26 |
| 9 |
|
Guaraní | 21 | 6 | 5 | 10 | 21:28 | -7 | 23 |
| 10 |
|
Sol de América | 21 | 5 | 5 | 11 | 21:33 | -12 | 20 |
| 11 |
|
Resistencia SC | 21 | 5 | 5 | 11 | 16:32 | -16 | 20 |
| 12 |
|
12 de Octubre de Itauguá | 21 | 3 | 2 | 16 | 16:37 | -21 | 11 |
| Copa Libertadores |
