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| 08.04.2016 | 18:00 | Anzhi Makhachkala | - | FK Rostov | 0:0 (0:0) | |
| 09.04.2016 | 12:30 | CSKA Moscú | - | Mordovia Saransk | 7:1 (5:0) | |
| 13:30 | FK Amkar Perm | - | Zenit | 0:2 (0:1) | ||
| 18:30 | Rubin Kazan | - | Dinamo Moskva | 4:1 (3:1) | ||
| 10.04.2016 | 13:30 | FK Ufa | - | Terek Grozny | 1:0 (1:0) | |
| 16:00 | FK Krasnodar | - | FK Ural | 6:0 (2:0) | ||
| 18:30 | Spartak Moskva | - | Kuban Krasnodar (1928-2018) | 2:2 (1:2) | ||
| 11.04.2016 | 17:00 | Krylia Sovetov | - | Lokomotiv Moskva | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moscú | 23 | 14 | 4 | 5 | 39:23 | 16 | 46 |
| 2 |
|
FK Rostov | 23 | 13 | 6 | 4 | 28:16 | 12 | 45 |
| 3 |
|
Zenit | 23 | 12 | 7 | 4 | 44:25 | 19 | 43 |
| 4 |
|
Lokomotiv Moskva | 23 | 12 | 6 | 5 | 36:26 | 10 | 42 |
| 5 |
|
FK Krasnodar | 23 | 11 | 7 | 5 | 41:22 | 19 | 40 |
| 6 |
|
Terek Grozny | 23 | 9 | 11 | 3 | 32:22 | 10 | 38 |
| 7 |
|
Spartak Moskva | 23 | 11 | 4 | 8 | 34:29 | 5 | 37 |
| 8 |
|
FK Ural | 23 | 9 | 7 | 7 | 35:38 | -3 | 34 |
| 9 |
|
Rubin Kazan | 23 | 8 | 3 | 12 | 28:32 | -4 | 27 |
| 10 |
|
FK Amkar Perm | 23 | 6 | 7 | 10 | 19:27 | -8 | 25 |
| 11 |
|
Dinamo Moskva | 23 | 5 | 9 | 9 | 24:35 | -11 | 24 |
| 12 |
|
Krylia Sovetov | 23 | 6 | 5 | 12 | 14:26 | -12 | 23 |
| 13 |
|
FK Ufa | 23 | 4 | 8 | 11 | 18:33 | -15 | 20 |
| 14 |
|
Kuban Krasnodar (1928-2018) | 23 | 3 | 11 | 9 | 30:34 | -4 | 20 |
| 15 |
|
Mordovia Saransk | 23 | 2 | 10 | 11 | 23:36 | -13 | 16 |
| 16 |
|
Anzhi Makhachkala | 23 | 3 | 7 | 13 | 22:43 | -21 | 16 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| EL Ronda previa | |
| Permanencia | |
| Descenso |
