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| 08.12.2018 | 10:30 | Krylia Sovetov | - | FK Rostov | 1:0 (1:0) | |
| 13:00 | CSKA Moscú | - | Enisey Krasnoyarsk | 2:1 (2:0) | ||
| 15:30 | Lokomotiv Moskva | - | FK Orenburg | 2:1 (0:1) | ||
| 18:00 | Anzhi Makhachkala | - | Spartak Moskva | 0:3 (0:1) | ||
| 09.12.2018 | 12:00 | Dinamo Moskva | - | FK Ural | 4:0 (2:0) | |
| 14:30 | FK Krasnodar | - | FK Ufa | 1:1 (1:1) | ||
| 17:00 | Zenit | - | Rubin Kazan | 1:2 (0:1) | ||
| 10.12.2018 | 17:30 | Akhmat Grozny | - | Arsenal Tula | 2:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit | 17 | 11 | 1 | 5 | 27:17 | 10 | 34 |
| 2 |
|
FK Krasnodar | 17 | 10 | 3 | 4 | 31:13 | 18 | 33 |
| 3 |
|
CSKA Moscú | 17 | 8 | 6 | 3 | 23:8 | 15 | 30 |
| 4 |
|
Spartak Moskva | 17 | 8 | 4 | 5 | 22:17 | 5 | 28 |
| 5 |
|
Lokomotiv Moskva | 17 | 8 | 4 | 5 | 23:17 | 6 | 28 |
| 6 |
|
FK Orenburg | 17 | 7 | 4 | 6 | 20:16 | 4 | 25 |
| 7 |
|
Rubin Kazan | 17 | 5 | 10 | 2 | 17:14 | 3 | 25 |
| 8 |
|
FK Rostov | 17 | 6 | 6 | 5 | 14:11 | 3 | 24 |
| 9 |
|
Akhmat Grozny | 17 | 6 | 5 | 6 | 15:17 | -2 | 23 |
| 10 |
|
FK Ural | 17 | 6 | 4 | 7 | 18:28 | -10 | 22 |
| 11 |
|
Dinamo Moskva | 17 | 4 | 8 | 5 | 16:13 | 3 | 20 |
| 12 |
|
Arsenal Tula | 17 | 5 | 5 | 7 | 23:25 | -2 | 20 |
| 13 |
|
Krylia Sovetov | 17 | 5 | 2 | 10 | 11:25 | -14 | 17 |
| 14 |
|
FK Ufa | 17 | 3 | 7 | 7 | 12:18 | -6 | 16 |
| 15 |
|
Anzhi Makhachkala | 17 | 4 | 3 | 10 | 9:25 | -16 | 15 |
| 16 |
|
Enisey Krasnoyarsk | 17 | 2 | 4 | 11 | 11:28 | -17 | 10 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| EL Ronda previa | |
| Permanencia | |
| Descenso |
