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| 12.04.2019 | 17:30 | Krylia Sovetov | - | Rubin Kazan | 1:0 (0:0) | |
| 13.04.2019 | 10:30 | Enisey Krasnoyarsk | - | FK Ufa | 0:0 (0:0) | |
| 13:00 | Arsenal Tula | - | FK Ural | 0:0 (0:0) | ||
| 13:00 | CSKA Moscú | - | FK Orenburg | 2:3 (2:2) | ||
| 18:30 | Akhmat Grozny | - | Lokomotiv Moskva | 1:3 (0:1) | ||
| 14.04.2019 | 13:00 | Dinamo Moskva | - | FK Krasnodar | 1:1 (0:0) | |
| 15:30 | Zenit | - | Anzhi Makhachkala | 5:0 (2:0) | ||
| 18:00 | FK Rostov | - | Spartak Moskva | 2:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit | 23 | 15 | 3 | 5 | 40:21 | 19 | 48 |
| 2 |
|
Lokomotiv Moskva | 23 | 12 | 6 | 5 | 33:21 | 12 | 42 |
| 3 |
|
FK Krasnodar | 23 | 12 | 6 | 5 | 41:18 | 23 | 42 |
| 4 |
|
CSKA Moscú | 23 | 11 | 7 | 5 | 33:15 | 18 | 40 |
| 5 |
|
Spartak Moskva | 23 | 10 | 6 | 7 | 29:24 | 5 | 36 |
| 6 |
|
FK Rostov | 23 | 9 | 8 | 6 | 21:15 | 6 | 35 |
| 7 |
|
Arsenal Tula | 23 | 8 | 8 | 7 | 28:25 | 3 | 32 |
| 8 |
|
FK Orenburg | 23 | 9 | 5 | 9 | 28:27 | 1 | 32 |
| 9 |
|
Rubin Kazan | 23 | 6 | 12 | 5 | 19:21 | -2 | 30 |
| 10 |
|
Akhmat Grozny | 23 | 8 | 6 | 9 | 22:26 | -4 | 30 |
| 11 |
|
Krylia Sovetov | 23 | 8 | 3 | 12 | 20:29 | -9 | 27 |
| 12 |
|
FK Ural | 23 | 7 | 6 | 10 | 23:35 | -12 | 27 |
| 13 |
|
Dinamo Moskva | 23 | 5 | 10 | 8 | 20:19 | 1 | 25 |
| 14 |
|
FK Ufa | 23 | 4 | 9 | 10 | 17:25 | -8 | 21 |
| 15 |
|
Anzhi Makhachkala | 23 | 5 | 4 | 14 | 11:40 | -29 | 19 |
| 16 |
|
Enisey Krasnoyarsk | 23 | 2 | 7 | 14 | 15:39 | -24 | 13 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| EL Ronda previa | |
| Permanencia | |
| Descenso |
