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| 07.04.2021 | 12:00 | FK Krasnodar | - | Lokomotiv Moskva | 4:0 (2:0) | |
| 12:00 | FK Sochi | - | CSKA Moskva | 1:3 (1:0) | ||
| 13:00 | Akhmat Grozny | - | FK Strogino Moskva | 3:2 (2:1) | ||
| 13:00 | FK Rostov | - | Zenit St. Petersburg | 1:2 (1:2) | ||
| 15:00 | Spartak Moskva | - | Rubin Kazan | 2:2 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 20 | 17 | 1 | 2 | 58:18 | 40 | 52 |
| 2 |
|
FK Krasnodar | 20 | 16 | 2 | 2 | 44:15 | 29 | 50 |
| 3 |
|
Zenit St. Petersburg | 20 | 16 | 2 | 2 | 56:16 | 40 | 50 |
| 4 |
|
Spartak Moskva | 20 | 13 | 4 | 3 | 39:18 | 21 | 43 |
| 5 |
|
Akhmat Grozny | 20 | 11 | 6 | 3 | 37:20 | 17 | 39 |
| 6 |
|
Lokomotiv Moskva | 20 | 11 | 3 | 6 | 39:17 | 22 | 36 |
| 7 |
|
Rubin Kazan | 20 | 9 | 5 | 6 | 26:19 | 7 | 32 |
| 8 |
|
FK Sochi | 20 | 7 | 7 | 6 | 26:23 | 3 | 28 |
| 9 |
|
FK Rostov | 20 | 6 | 6 | 8 | 32:32 | 0 | 24 |
| 10 |
|
FK Strogino Moskva | 20 | 7 | 3 | 10 | 32:38 | -6 | 24 |
