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| 06.10.2021 | 13:30 | Adıyamanspor | - | Niğde Anadolu FK | 0:1 (0:1) | |
| 13:30 | Kahramanmaraşspor | - | Çorum FK | 0:2 (0:0) | ||
| 13:30 | Sivas Belediyespor | - | Sarıyer SK | 3:0 (1:0) | ||
| 14:00 | Etimesgut Belediyespor | - | Bayburt İl Özel İdare | 0:2 (0:1) | ||
| 14:30 | Ergene Velimeşe | - | Ankaraspor | 0:3 (0:1) | ||
| 14:30 | Serik Belediyespor | - | Bodrum FK | 2:1 (1:1) | ||
| 14:30 | Turgutluspor | - | Vanspor FK | 1:3 (0:1) | ||
| 18:00 | Afjet Afyonspor | - | Inegölspor | 4:2 (1:1) | ||
| 18:00 | Diyarbekirspor | - | Hekimoğlu Trabzon | 0:1 (0:0) | ||
| 18:00 | Sakaryaspor | - | Somaspor | 3:0 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sivas Belediyespor | 6 | 4 | 2 | 0 | 12:1 | 11 | 14 |
| 2 |
|
Hekimoğlu Trabzon | 6 | 4 | 2 | 0 | 12:3 | 9 | 14 |
| 3 |
|
Vanspor FK | 6 | 4 | 2 | 0 | 12:6 | 6 | 14 |
| 4 |
|
Bayburt İl Özel İdare | 6 | 4 | 2 | 0 | 8:2 | 6 | 14 |
| 5 |
|
Ankaraspor | 6 | 4 | 1 | 1 | 15:4 | 11 | 13 |
| 6 |
|
Bodrum FK | 6 | 4 | 0 | 2 | 11:4 | 7 | 12 |
| 7 |
|
Çorum FK | 6 | 3 | 3 | 0 | 8:1 | 7 | 12 |
| 8 |
|
Sakaryaspor | 6 | 3 | 3 | 0 | 7:1 | 6 | 12 |
| 9 |
|
Etimesgut Belediyespor | 6 | 3 | 1 | 2 | 10:8 | 2 | 10 |
| 10 |
|
Somaspor | 6 | 3 | 1 | 2 | 10:9 | 1 | 10 |
| 11 |
|
Afjet Afyonspor | 6 | 2 | 3 | 1 | 13:11 | 2 | 9 |
| 12 |
|
Serik Belediyespor | 6 | 3 | 0 | 3 | 7:9 | -2 | 9 |
| 13 |
|
Inegölspor | 6 | 2 | 2 | 2 | 11:10 | 1 | 8 |
| 14 |
|
Sarıyer SK | 6 | 2 | 1 | 3 | 7:10 | -3 | 7 |
| 15 |
|
Diyarbekirspor | 6 | 1 | 1 | 4 | 5:9 | -4 | 4 |
| 16 |
|
Niğde Anadolu FK | 6 | 1 | 0 | 5 | 3:17 | -14 | 3 |
| 17 |
|
Turgutluspor | 6 | 0 | 1 | 5 | 4:12 | -8 | 1 |
| 18 |
|
Ergene Velimeşe | 6 | 0 | 1 | 5 | 2:16 | -14 | 1 |
| 19 |
|
Adıyamanspor | 6 | 0 | 0 | 6 | 4:15 | -11 | 0 |
| 20 |
|
Kahramanmaraşspor | 6 | 0 | 0 | 6 | 3:16 | -13 | 0 |
| Ascenso | |
| Playoff | |
| Descenso |
