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| 29.10.2021 | 19:00 | Trabzonspor | - | Çaykur Rizespor | 2:1 (1:1) | |
| 30.10.2021 | 12:30 | Kasımpaşa SK | - | Yeni Malatyaspor | 2:0 (0:0) | |
| 15:00 | Altay Izmir | - | Sivasspor | 1:1 (1:1) | ||
| 15:00 | Hatayspor | - | Beşiktaş | 1:0 (1:0) | ||
| 18:00 | Konyaspor | - | Fenerbahçe | 2:1 (2:0) | ||
| 31.10.2021 | 11:30 | Kayserispor | - | Fatih Karagümrük | 2:1 (0:1) | |
| 14:00 | Alanyaspor | - | Göztepe | 2:2 (1:0) | ||
| 17:00 | Galatasaray | - | Gaziantep FK | 2:0 (1:0) | ||
| 01.11.2021 | 18:00 | Giresunspor | - | Antalyaspor | 1:2 (0:1) | |
| 18:00 | İstanbul Başakşehir | - | Adana Demirspor | 2:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Trabzonspor | 11 | 8 | 3 | 0 | 22:10 | 12 | 27 |
| 2 |
|
Hatayspor | 11 | 7 | 2 | 2 | 20:8 | 12 | 23 |
| 3 |
|
Alanyaspor | 11 | 6 | 3 | 2 | 18:17 | 1 | 21 |
| 4 |
|
Beşiktaş | 11 | 6 | 2 | 3 | 20:13 | 7 | 20 |
| 5 |
|
Konyaspor | 11 | 5 | 5 | 1 | 16:10 | 6 | 20 |
| 6 |
|
Galatasaray | 11 | 6 | 2 | 3 | 17:14 | 3 | 20 |
| 7 |
|
Fenerbahçe | 11 | 6 | 1 | 4 | 15:13 | 2 | 19 |
| 8 |
|
Fatih Karagümrük | 11 | 5 | 3 | 3 | 17:14 | 3 | 18 |
| 9 |
|
Altay Izmir | 11 | 5 | 1 | 5 | 17:17 | 0 | 16 |
| 10 |
|
İstanbul Başakşehir | 11 | 5 | 0 | 6 | 15:14 | 1 | 15 |
| 11 |
|
Kayserispor | 11 | 4 | 2 | 5 | 15:18 | -3 | 14 |
| 12 |
|
Adana Demirspor | 11 | 3 | 4 | 4 | 16:17 | -1 | 13 |
| 13 |
|
Sivasspor | 11 | 2 | 6 | 3 | 15:13 | 2 | 12 |
| 14 |
|
Antalyaspor | 11 | 3 | 3 | 5 | 13:17 | -4 | 12 |
| 15 |
|
Gaziantep FK | 11 | 3 | 3 | 5 | 12:16 | -4 | 12 |
| 16 |
|
Yeni Malatyaspor | 11 | 4 | 0 | 7 | 11:19 | -8 | 12 |
| 17 |
|
Kasımpaşa SK | 11 | 2 | 3 | 6 | 12:16 | -4 | 9 |
| 18 |
|
Göztepe | 11 | 2 | 3 | 6 | 11:16 | -5 | 9 |
| 19 |
|
Giresunspor | 11 | 2 | 3 | 6 | 7:12 | -5 | 9 |
| 20 |
|
Çaykur Rizespor | 11 | 1 | 1 | 9 | 9:24 | -15 | 4 |
| Champions League | |
| CL Ronda previa | |
| ECL Ronda previa | |
| Descenso |
