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| 20.08.2010 | 18:00 | FK Obolon | - | Zorya Lugansk | 1:0 (1:0) | |
| 21.08.2010 | 18:00 | Volyn Lutsk | - | Shakhtar Donetsk | 0:1 (0:0) | |
| 18:00 | FK Illichivets | - | Arsenal Kiev | 2:2 (1:1) | ||
| 20:00 | Metalurh Donetsk | - | Vorskla Poltava | 2:0 (1:0) | ||
| 22.08.2010 | 18:00 | Tavriya Simferopol (1958-2014) | - | Metalurg Zaporizhya | 2:0 (0:0) | |
| 19:15 | Dinamo Kiev | - | Dnipro Dnipropetrovsk | 0:0 (0:0) | ||
| 19:30 | Karpaty Lviv | - | PFK Sevastopol | 2:1 (1:0) | ||
| 20:00 | Metalist Kharkiv | - | FK Krivbas (old) | 3:4 (2:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Shakhtar Donetsk | 7 | 6 | 1 | 0 | 14:2 | 12 | 19 |
| 2 |
|
Dnipro Dnipropetrovsk | 7 | 5 | 1 | 1 | 12:2 | 10 | 16 |
| 3 |
|
Dinamo Kiev | 7 | 4 | 2 | 1 | 11:7 | 4 | 14 |
| 4 |
|
Vorskla Poltava | 7 | 4 | 1 | 2 | 12:8 | 4 | 13 |
| 5 |
|
Karpaty Lviv | 7 | 3 | 2 | 2 | 7:6 | 1 | 11 |
| 6 |
|
Tavriya Simferopol (1958-2014) | 7 | 3 | 1 | 3 | 9:6 | 3 | 10 |
| 7 |
|
Metalist Kharkiv | 7 | 3 | 1 | 3 | 11:9 | 2 | 10 |
| 8 |
|
Metalurh Donetsk | 7 | 3 | 1 | 3 | 8:7 | 1 | 10 |
| 9 |
|
FK Krivbas (old) | 7 | 2 | 3 | 2 | 7:10 | -3 | 9 |
| 10 |
|
Arsenal Kiev | 7 | 2 | 2 | 3 | 8:9 | -1 | 8 |
| 11 |
|
FK Obolon | 7 | 2 | 2 | 3 | 6:11 | -5 | 8 |
| 12 |
|
FK Illichivets | 7 | 1 | 4 | 2 | 9:12 | -3 | 7 |
| 13 |
|
Zorya Lugansk | 7 | 1 | 3 | 3 | 5:8 | -3 | 6 |
| 14 |
|
Volyn Lutsk | 7 | 1 | 2 | 4 | 2:9 | -7 | 5 |
| 15 |
|
PFK Sevastopol | 7 | 1 | 2 | 4 | 2:11 | -9 | 5 |
| 16 |
|
Metalurg Zaporizhya | 7 | 0 | 2 | 5 | 2:8 | -6 | 2 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
