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| 19.10.2025 | 00:00 | Atlanta United FC | - | D.C. United | -:- | |
| 00:00 | Charlotte FC | - | Philadelphia Union | -:- | ||
| 00:00 | Columbus Crew | - | New York RB | -:- | ||
| 00:00 | FC Cincinnati | - | CF Montréal | -:- | ||
| 00:00 | Nashville SC | - | Inter Miami CF | -:- | ||
| 00:00 | New England Revolution | - | Chicago Fire | -:- | ||
| 00:00 | New York City FC | - | Seattle Sounders | -:- | ||
| 00:00 | Toronto FC | - | Orlando City | -:- | ||
| 03:00 | Colorado Rapids | - | Los Angeles FC | -:- | ||
| 03:00 | Los Angeles Galaxy | - | Minnesota United FC | -:- | ||
| 03:00 | Portland Timbers | - | San Diego FC | -:- | ||
| 03:00 | San Jose Earthquakes | - | Austin FC | -:- | ||
| 03:00 | Sporting Kansas City | - | Houston Dynamo | -:- | ||
| 03:00 | St. Louis City SC | - | Real Salt Lake | -:- | ||
| 03:00 | Vancouver Whitecaps | - | FC Dallas | -:- |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| 1 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew | 7 | 4 | 3 | 0 | 10:5 | 5 | 15 |
| 2 |
|
Inter Miami CF | 6 | 4 | 2 | 0 | 12:6 | 6 | 14 |
| 3 |
|
Philadelphia Union | 7 | 4 | 1 | 2 | 13:8 | 5 | 13 |
| 4 |
|
Charlotte FC | 7 | 4 | 1 | 2 | 12:7 | 5 | 13 |
| 5 |
|
FC Cincinnati | 7 | 4 | 1 | 2 | 9:9 | 0 | 13 |
| 6 |
|
Orlando City | 7 | 3 | 2 | 2 | 15:12 | 3 | 11 |
| 7 |
|
Chicago Fire | 7 | 3 | 2 | 2 | 14:12 | 2 | 11 |
| 8 |
|
New York RB | 7 | 3 | 2 | 2 | 9:7 | 2 | 11 |
| 9 |
|
Nashville SC | 7 | 3 | 1 | 3 | 10:7 | 3 | 10 |
| 10 |
|
Atlanta United FC | 7 | 2 | 3 | 2 | 11:12 | -1 | 9 |
| 11 |
|
New York City FC | 7 | 2 | 2 | 3 | 10:11 | -1 | 8 |
| 12 |
|
D.C. United | 7 | 1 | 3 | 3 | 9:17 | -8 | 6 |
| 13 |
|
New England Revolution | 6 | 1 | 1 | 4 | 3:7 | -4 | 4 |
| 14 |
|
Toronto FC | 7 | 0 | 3 | 4 | 7:13 | -6 | 3 |
| 15 |
|
CF Montréal | 7 | 0 | 2 | 5 | 4:12 | -8 | 2 |
| 2 | |||||||||
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Vancouver Whitecaps | 7 | 5 | 1 | 1 | 12:5 | 7 | 16 |
| 2 |
|
San Diego FC | 7 | 4 | 2 | 1 | 13:6 | 7 | 14 |
| 3 |
|
Minnesota United FC | 7 | 4 | 2 | 1 | 11:7 | 4 | 14 |
| 4 |
|
Austin FC | 7 | 4 | 1 | 2 | 5:3 | 2 | 13 |
| 5 |
|
Portland Timbers | 7 | 3 | 2 | 2 | 9:8 | 1 | 11 |
| 6 |
|
FC Dallas | 7 | 3 | 2 | 2 | 10:10 | 0 | 11 |
| 7 |
|
Colorado Rapids | 7 | 3 | 2 | 2 | 8:9 | -1 | 11 |
| 8 |
|
San Jose Earthquakes | 7 | 3 | 1 | 3 | 15:10 | 5 | 10 |
| 9 |
|
Los Angeles FC | 7 | 3 | 0 | 4 | 8:10 | -2 | 9 |
| 10 |
|
Real Salt Lake | 7 | 3 | 0 | 4 | 7:11 | -4 | 9 |
| 11 |
|
St. Louis City SC | 7 | 2 | 2 | 3 | 4:4 | 0 | 8 |
| 12 |
|
Seattle Sounders | 7 | 1 | 3 | 3 | 8:11 | -3 | 6 |
| 13 |
|
Houston Dynamo | 7 | 1 | 2 | 4 | 5:11 | -6 | 5 |
| 14 |
|
Sporting Kansas City | 7 | 1 | 1 | 5 | 8:12 | -4 | 4 |
| 15 |
|
Los Angeles Galaxy | 7 | 0 | 2 | 5 | 5:14 | -9 | 2 |
| Playoff | |
| Clasificación | |
| Playoff | |
| Clasificación |
