| 3. Jornada | 14.08.2021 | Cove Rangers | - | East Fife FC | 5:2 | ||||
| 4. Jornada | 21.08.2021 | East Fife FC | - | Montrose FC | 0:2 | ||||
| 5. Jornada | 28.08.2021 | East Fife FC | - | Peterhead FC | 3:0 | ||||
| 6. Jornada | 11.09.2021 | Dumbarton FC | - | East Fife FC | 5:0 | ||||
| 7. Jornada | 18.09.2021 | Airdrieonians FC | - | East Fife FC | 3:0 | ||||
| 8. Jornada | 25.09.2021 | East Fife FC | - | Clyde FC | 0:2 | ||||
| 9. Jornada | 02.10.2021 | Falkirk FC | - | East Fife FC | 2:1 | ||||
| 15. Jornada | 20.11.2021 | Clyde FC | - | East Fife FC | 3:1 |  |
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| 17. Jornada | 11.12.2021 | Peterhead FC | - | East Fife FC | 1:1 | ||||
| 19. Jornada | 26.12.2021 | Cove Rangers | - | East Fife FC | 4:2 | ||||
| 20. Jornada | 02.01.2022 | East Fife FC | - | Montrose FC | 0:2 | ||||
| 21. Jornada | 08.01.2022 | Airdrieonians FC | - | East Fife FC | 3:0 | ||||
| 23. Jornada | 29.01.2022 | East Fife FC | - | Peterhead FC | 0:0 | ||||
| 24. Jornada | 05.02.2022 | East Fife FC | - | Clyde FC | 0:0 | |
Escocia