| 3. Jornada | 29.01.2021 | Boston River | - | Cerro Largo | 2:1 | ||||
| 4. Jornada | 02.02.2021 | Cerro Largo | - | Deportivo Maldonado | 1:2 | ||||
| 5. Jornada | 06.02.2021 | Rentistas | - | Cerro Largo | 2:1 |  |
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| 6. Jornada | 10.02.2021 | Liverpool | - | Cerro Largo | 3:2 | ||||
| 8. Jornada | 17.02.2021 | Cerro Largo | - | Peñarol | 1:1 | ||||
| 9. Jornada | 20.02.2021 | River Plate | - | Cerro Largo | 2:0 | ||||
| 10. Jornada | 01.03.2021 | Montevideo City Torque | - | Cerro Largo | 0:0 | |
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| 11. Jornada | 07.03.2021 | Cerro Largo | - | Plaza Colonia | 3:1 | ||||
| 12. Jornada | 14.03.2021 | Cerro Largo | - | Progreso | 1:0 | |
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| 13. Jornada | 21.03.2021 | Fénix | - | Cerro Largo | 1:0 |  |
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| 15. Jornada | 29.03.2021 | Cerro Largo | - | Defensor Sporting | 0:0 |
Argentina