| 4. Jornada | 06.02.2022 | Gallos Blancos [Sub 18] | - | Puebla FC [Sub 18] | 3:1 | ||||
| 5. Jornada | 11.02.2022 | Puebla FC [Sub 18] | - | Atlas Guadalajara [Sub 18] | 0:0 | ||||
| 12. Jornada | 03.04.2022 | Deportivo Toluca [Sub 18] | - | Puebla FC [Sub 18] | 0:1 | ||||
| 14. Jornada | 16.04.2022 | Club León [Sub 18] | - | Puebla FC [Sub 18] | 5:4 | ||||
| 15. Jornada | 19.04.2022 | CF Pachuca [Sub 18] | - | Puebla FC [Sub 18] | 3:0 | ||||
| 16. Jornada | 22.04.2022 | Puebla FC [Sub 18] | - | Club Necaxa [Sub 18] | 1:4 |
México