| Tercera ronda | 13.12.2021 | Manchester United [Sub 18] | - | Scunthorpe United [Sub 18] | 4:2 |  |
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| Cuarta Ronda | 13.01.2022 | Reading FC [Sub 18] | - | Manchester United [Sub 18] | 1:3 | ||||
| Octavos de final | 09.02.2022 | Manchester United [Sub 18] | - | Everton FC [Sub 18] | 4:1 | |
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| Cuartos de final | 24.02.2022 | Manchester United [Sub 18] | - | Leicester City [Sub 18] | 2:1 | |
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| Semifinales | 09.03.2022 | Manchester United [Sub 18] | - | Wolverhampton Wanderers [Sub 18] | 3:0 | |
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| Final | 11.05.2022 | Manchester United [Sub 18] | - | Nottingham Forest [Sub 18] | 3:1 | |
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España
