| 1. Jornada | 06.02.2022 | Independiente Petrolero | - | Always Ready | 1:2 | ||||
| 2. Jornada | 13.02.2022 | Real Tomayapo | - | Independiente Petrolero | 1:1 | ||||
| 3. Jornada | 20.02.2022 | Independiente Petrolero | - | Bolívar | 1:0 | ||||
| 4. Jornada | 28.02.2022 | Jorge Wilstermann | - | Independiente Petrolero | 1:0 | ||||
| 5. Jornada | 06.03.2022 | Independiente Petrolero | - | Blooming | 2:3 | ||||
| 6. Jornada | 13.03.2022 | Universitario de Sucre | - | Independiente Petrolero | 1:2 | ||||
| 7. Jornada | 02.04.2022 | Universitario de Vinto | - | Independiente Petrolero | 2:2 | ||||
| 9. Jornada | 16.04.2022 | Always Ready | - | Independiente Petrolero | 1:1 |  |
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| 10. Jornada | 20.04.2022 | Independiente Petrolero | - | Real Tomayapo | 1:1 | ||||
| 11. Jornada | 23.04.2022 | Bolívar | - | Independiente Petrolero | 3:1 |
Bolivia