| 2. Jornada | 21.01.2021 | Deportivo Maldonado | - | Liverpool | 2:4 |  |
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| 3. Jornada | 30.01.2021 | Progreso | - | Liverpool | 0:4 | ||||
| 5. Jornada | 06.02.2021 | Fénix | - | Liverpool | 0:2 | ||||
| 12. Jornada | 14.03.2021 | Liverpool | - | River Plate | 3:2 | ||||
| 14. Jornada | 24.03.2021 | Liverpool | - | Montevideo City Torque | 4:1 | ||||
| 15. Jornada | 29.03.2021 | Boston River | - | Liverpool | 1:0 |
Uruguay