| 1. Jornada | 21.08.2021 | Paphos FC | - | APOEL Nikosia | 4:0 | ||||
| 2. Jornada | 13.09.2021 | AEL Limassol | - | Paphos FC | 4:0 | ||||
| 3. Jornada | 18.09.2021 | Paphos FC | - | AEK Larnaca | 1:1 |  |
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| 4. Jornada | 26.09.2021 | Omonia Nikosia | - | Paphos FC | 1:1 | |
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| 10. Jornada | 20.11.2021 | Paphos FC | - | Ethnikos Achna | 3:0 | ||||
| 12. Jornada | 05.12.2021 | APOEL Nikosia | - | Paphos FC | 1:1 | |
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| 15. Jornada | 05.01.2022 | Paphos FC | - | Omonia Nikosia | 1:1 |
Chipre