| 6. Jornada | 05.08.2012 | Chicago Fire | - | Toronto FC | 2:1 | ||||
| 6. Jornada | 13.08.2012 | Philadelphia Union | - | Chicago Fire | 1:3 | ||||
| 6. Jornada | 19.08.2012 | Chicago Fire | - | New England Revolution | 2:1 | ||||
| 6. Jornada | 23.08.2012 | D.C. United | - | Chicago Fire | 4:2 | ||||
| 7. Jornada | 03.09.2012 | Chicago Fire | - | Houston Dynamo | 3:1 | ||||
| 7. Jornada | 13.09.2012 | Toronto FC | - | Chicago Fire | 1:2 |  |
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| 7. Jornada | 16.09.2012 | Chicago Fire | - | Impact de Montréal | 3:1 | |
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| 7. Jornada | 23.09.2012 | Chicago Fire | - | Columbus Crew | 2:1 | ||||
| 7. Jornada | 29.09.2012 | Sporting Kansas City | - | Chicago Fire | 2:0 | ||||
| 8. Jornada | 04.10.2012 | Chicago Fire | - | Philadelphia Union | 1:3 | ||||
| 8. Jornada | 06.10.2012 | New York RB | - | Chicago Fire | 0:2 | ||||
| 8. Jornada | 21.10.2012 | New England Revolution | - | Chicago Fire | 1:0 | ||||
| 8. Jornada | 27.10.2012 | Chicago Fire | - | D.C. United | 1:1 |
Uruguay