| 4. Jornada | 02.08.2018 | The Strongest | - | Destroyers | 4:1 | ||||
| 5. Jornada | 04.08.2018 | Destroyers | - | Jorge Wilstermann | 0:0 |  |
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| 9. Jornada | 03.09.2018 | Oriente Petrolero | - | Destroyers | 1:0 | ||||
| 10. Jornada | 15.09.2018 | Bolívar | - | Destroyers | 5:1 | |
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| 11. Jornada | 19.09.2018 | Destroyers | - | Royal Pari | 2:0 | |
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| 12. Jornada | 22.09.2018 | Destroyers | - | Club Aurora | 1:0 | ||||
| 13. Jornada | 29.09.2018 | Universitario de Sucre | - | Destroyers | 1:0 | |
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| 14. Jornada | 07.10.2018 | Destroyers | - | Sport Boys Warnes | 2:3 | ||||
| 21. Jornada | 14.10.2018 | Club San José | - | Destroyers | 3:1 | ||||
| 15. Jornada | 23.10.2018 | Blooming | - | Destroyers | 1:0 | |
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| 17. Jornada | 29.10.2018 | Destroyers | - | The Strongest | 0:1 | |
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| 18. Jornada | 04.11.2018 | Jorge Wilstermann | - | Destroyers | 2:1 | |
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| 19. Jornada | 10.11.2018 | Destroyers | - | CD Guabirá | 1:2 | ||||
| 23. Jornada | 17.11.2018 | Royal Pari | - | Destroyers | 1:1 | |
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| 20. Jornada | 24.11.2018 | Real Potosí | - | Destroyers | 3:2 | ||||
| 22. Jornada | 04.12.2018 | Destroyers | - | Oriente Petrolero | 0:0 |
Brasil