| 2. Jornada | 12.09.2021 | Doxa Katokopias | - | Anorthosis Famagusta | 2:0 | ||||
| 4. Jornada | 25.09.2021 | Aris Limassol | - | Anorthosis Famagusta | 3:2 | ||||
| 6. Jornada | 17.10.2021 | AEL Limassol | - | Anorthosis Famagusta | 2:1 | ||||
| 8. Jornada | 29.10.2021 | Omonia Nikosia | - | Anorthosis Famagusta | 0:1 |  |
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| 1. Jornada | 22.12.2021 | PAEEK | - | Anorthosis Famagusta | 0:2 | ||||
| 20. Jornada | 06.02.2022 | Paphos FC | - | Anorthosis Famagusta | 1:1 | |
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| 15. Jornada | 10.02.2022 | Anorthosis Famagusta | - | Aris Limassol | 3:1 |
Chipre