| Octavos de final | 29.09.2022 | Defensor Sporting | - | River Plate | 2:0 |  |
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| Cuartos de final | 04.10.2022 | Defensor Sporting | - | Liverpool | 3:0 | |
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| Semifinales | 26.10.2022 | Progreso | - | Defensor Sporting | 1:1 | ||||
| Semifinales | 04.11.2022 | Defensor Sporting | - | Progreso | 3:1 | |
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| Final | 13.11.2022 | Defensor Sporting | - | La Luz | 1:0 |  |
Uruguay