| 3. Jornada | 14.08.2022 | Montevideo City Torque | - | Defensor Sporting | 0:2 | ||||
| 8. Jornada | 16.09.2022 | Defensor Sporting | - | Cerro Largo | 0:1 | ||||
| 9. Jornada | 20.09.2022 | Fénix | - | Defensor Sporting | 0:0 |  |
|||
| 11. Jornada | 02.10.2022 | Defensor Sporting | - | Albion | 2:0 | ||||
| 12. Jornada | 09.10.2022 | Nacional | - | Defensor Sporting | 1:1 | ||||
| 13. Jornada | 13.10.2022 | Defensor Sporting | - | Danubio | 1:1 | ||||
| 14. Jornada | 15.10.2022 | Deportivo Maldonado | - | Defensor Sporting | 0:0 | ||||
| 15. Jornada | 22.10.2022 | Defensor Sporting | - | Rentistas | 2:3 |
Uruguay