| 1. Jornada | 20.09.2021 | Deportivo Dongu | - | Montañeses FC | 2:3 | ||||
| 2. Jornada | 25.09.2021 | Leviatán FC | - | Deportivo Dongu | 1:1 | ||||
| 3. Jornada | 02.10.2021 | Deportivo Dongu | - | Sporting Canamy | 1:2 |  |
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| 5. Jornada | 13.10.2021 | Deportivo Dongu | - | Lobos ULMX | 2:2 | ||||
| 6. Jornada | 17.10.2021 | Reboceros de La Piedad | - | Deportivo Dongu | 2:2 |  |
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| 12. Jornada | 20.11.2021 | Deportivo Dongu | - | CD Zap | 0:2 | ||||
| 13. Jornada | 27.11.2021 | Inter de Querétaro | - | Deportivo Dongu | 3:0 |
México