| 5. Jornada | 25.09.2021 | 1. FC Nürnberg [Juvenil] | - | Darmstadt [Juvenil] | 1:2 | ||||
| 6. Jornada | 02.10.2021 | Darmstadt [Juvenil] | - | SpVgg Greuther Fürth [Juvenil] | 0:0 | ||||
| 7. Jornada | 17.10.2021 | Mainz [Juvenil] | - | Darmstadt [Juvenil] | 0:0 | ||||
| 9. Jornada | 31.10.2021 | FC-Astoria Walldorf [Juvenil] | - | Darmstadt [Juvenil] | 1:1 | ||||
| 10. Jornada | 20.11.2021 | Darmstadt [Juvenil] | - | Ingolstadt [Juvenil] | 0:0 | ||||
| 12. Jornada | 04.12.2021 | Darmstadt [Juvenil] | - | 1. FC Kaiserslautern [Juvenil] | 1:3 | ||||
| 15. Jornada | 19.02.2022 | Darmstadt [Juvenil] | - | 1. FC Heidenheim 1846 [Juvenil] | 0:0 | ||||
| 16. Jornada | 26.02.2022 | Kickers Offenbach [Juvenil] | - | Darmstadt [Juvenil] | 0:4 | ||||
| 17. Jornada | 05.03.2022 | Darmstadt [Juvenil] | - | SC Freiburg [Juvenil] | 3:2 | ||||
| 18. Jornada | 20.04.2022 | SSV Ulm 1846 [Juvenil] | - | Darmstadt [Juvenil] | 0:2 | ||||
| 20. Jornada | 23.04.2022 | Augsburgo [Juvenil] | - | Darmstadt [Juvenil] | 4:1 | ||||
| 21. Jornada | 30.04.2022 | Darmstadt [Juvenil] | - | 1. FC Saarbrücken [Juvenil] | 0:2 |
Grecia