| 1. Jornada | 14.08.2021 | Fortuna Sittard | - | FC Twente | 2:1 | ||||
| 3. Jornada | 27.08.2021 | Fortuna Sittard | - | RKC Waalwijk | 2:2 | ||||
| 11. Jornada | 31.10.2021 | Go Ahead Eagles | - | Fortuna Sittard | 4:3 | ||||
| 12. Jornada | 07.11.2021 | Fortuna Sittard | - | PSV | 1:4 | ||||
| 13. Jornada | 20.11.2021 | Heracles Almelo | - | Fortuna Sittard | 3:1 |  |
|||
| 14. Jornada | 27.11.2021 | Fortuna Sittard | - | FC Groningen | 1:4 | ||||
| 15. Jornada | 05.12.2021 | Feyenoord | - | Fortuna Sittard | 5:0 | ||||
| 18. Jornada | 22.12.2021 | AFC Ajax | - | Fortuna Sittard | 5:0 | ||||
| 19. Jornada | 16.01.2022 | Fortuna Sittard | - | AZ Alkmaar | 1:2 | ||||
| 20. Jornada | 23.01.2022 | RKC Waalwijk | - | Fortuna Sittard | 2:1 | ||||
| 27. Jornada | 20.03.2022 | PSV | - | Fortuna Sittard | 5:0 | ||||
| 23. Jornada | 16.04.2022 | Fortuna Sittard | - | Sparta Rotterdam | 3:0 | ||||
| 31. Jornada | 01.05.2022 | Fortuna Sittard | - | Feyenoord | 1:3 | ||||
| 32. Jornada | 07.05.2022 | FC Twente | - | Fortuna Sittard | 1:2 |
Alemania
Kosovo