| 8. Jornada | 18.09.2021 | Colchester United | - | Crawley Town | 0:1 | ||||
| 9. Jornada | 25.09.2021 | Swindon Town | - | Colchester United | 0:0 | ||||
| 10. Jornada | 02.10.2021 | Colchester United | - | Salford City | 0:2 | ||||
| 13. Jornada | 19.10.2021 | Colchester United | - | Bristol Rovers | 1:1 |  |
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| 15. Jornada | 30.10.2021 | Colchester United | - | Scunthorpe United | 2:1 |  |
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| 17. Jornada | 20.11.2021 | Stevenage FC | - | Colchester United | 1:0 | |
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| 18. Jornada | 23.11.2021 | Colchester United | - | Exeter City | 3:1 | ||||
| 19. Jornada | 26.11.2021 | Colchester United | - | Newport County | 1:1 | ||||
| 20. Jornada | 08.12.2021 | Bradford City | - | Colchester United | 0:0 | ||||
| 21. Jornada | 11.12.2021 | Walsall FC | - | Colchester United | 3:0 | ||||
| 25. Jornada | 01.01.2022 | Crawley Town | - | Colchester United | 3:1 |
Inglaterra